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Cyclophosphamide shortage status

Widespread shortage Tier 3: critical

Source: Health Canada shortage reports · Updated Jul 9, 2026

Cyclophosphamide is in a widespread shortage in Canada. 4 of 10 reported products are affected, and Health Canada has designated this a Tier 3 (most serious) shortage. The latest manufacturer estimate for full recovery is Jun 19, 2026.
Products affected
4 of 10
In shortage since
Jan 10, 2026
Est. full return
Jun 19, 2026
Reports on file
16
Talk to your pharmacist. Pharmacists can often substitute another manufacturer's version, a different strength, or (in most provinces) adapt or renew a prescription on the spot. Your free provincial health line is 811.

Reports by product

Active shortage
CYCLOPHOSPHAMIDE FOR INJECTION USP
1000MG · POWDER FOR SOLUTION · ANDONE PHARMACEUTICAL INC
DIN 02546736 · since Feb 23, 2026, est. end Jun 19, 2026 · Demand increase for the drug.
Active shortage
CYCLOPHOSPHAMIDE FOR INJECTION USP
2000MG · POWDER FOR SOLUTION · ANDONE PHARMACEUTICAL INC
DIN 02546744 · since Feb 23, 2026, est. end Jun 19, 2026 · Demand increase for the drug.
Active shortage
PROCYTOX
2000MG · POWDER FOR SOLUTION · BAXTER CORPORATION
DIN 02241800 · since Jan 10, 2026, no end estimate · Disruption of the manufacture of the drug.
Active shortage
PROCYTOX
500MG · POWDER FOR SOLUTION · BAXTER CORPORATION
DIN 02241798 · since Feb 13, 2026, no end estimate · Disruption of the manufacture of the drug.
Anticipated
PROCYTOX
1000MG · POWDER FOR SOLUTION · BAXTER CORPORATION
DIN 02241799 · Disruption of the manufacture of the drug.
Anticipated
CYCLOPHOSPHAMIDE FOR INJECTION USP
1000MG · POWDER FOR SOLUTION · STERIMAX INC
DIN 02547686 · Demand increase for the drug.
Anticipated
CYCLOPHOSPHAMIDE FOR INJECTION USP
2000MG · POWDER FOR SOLUTION · STERIMAX INC
DIN 02547694 · Demand increase for the drug.
To be discontinued
PROCYTOX TAB 25MG
25MG · TABLET · BAXTER CORPORATION
DIN 02241795
To be discontinued
PROCYTOX
200MG · POWDER FOR SOLUTION · BAXTER CORPORATION
DIN 02241797
Resolved
PROCYTOX TAB 50MG
50MG · TABLET · BAXTER CORPORATION
DIN 02241796 · ended Dec 16, 2025 · Delay in shipping of the drug.
Resolved
PROCYTOX
2000MG · POWDER FOR SOLUTION · BAXTER CORPORATION
DIN 02241800 · ended May 2, 2024 · Other (Please describe in comments)
Resolved
PROCYTOX
2000MG · POWDER FOR SOLUTION · BAXTER CORPORATION
DIN 02241800 · ended Feb 27, 2024 · Disruption of the manufacture of the drug.

Showing 12 of 16 reports. All reports are on file with Health Canada.

What's happening

Cyclophosphamide is currently affected by 4 active shortage reports filed with Health Canada by ANDONE PHARMACEUTICAL INC, BAXTER CORPORATION.

The reported causes are: demand increase for the drug; disruption of the manufacture of the drug. Manufacturers must report shortages, but end-date estimates are their own projections and often move.

Health Canada has flagged this as a Tier 3 shortage, its most serious category, meaning the shortage has the greatest potential impact on the health system and alternatives are limited.

If your usual product is affected, a pharmacist is the fastest route to a solution: they can dispense an unaffected manufacturer's equivalent when one exists, and in most provinces can adapt doses or substitute a therapeutic alternative without a new appointment.

Cyclophosphamide is classified under “ALKYLATINGAGENTS” (ATC L01AA).

Recent changes

Common questions

When will Cyclophosphamide be back in stock in Canada?

The latest manufacturer estimate is Jun 19, 2026. Estimates are self-reported and often slip; this page updates automatically when they change.

Why is Cyclophosphamide in shortage?

See the reports above; manufacturers must state a reason (most commonly manufacturing disruption or a surge in demand) when filing with Health Canada.

What can my pharmacist do about it?

Often quite a lot: substitute an equivalent product from an unaffected manufacturer, adjust quantities, or in most provinces adapt or renew prescriptions on the spot. Call your pharmacy before visiting, and call 811 for free health advice.

Related drugs (alkylatingagents)

Widespread shortageIfosfamide2 of 2 reported products affected · est. return Sep 30, 2026Partial shortageBendamustine2 of 8 reported products affected · est. return Jan 1, 2025Partial shortageBusulfan1 of 4 reported products affected · est. return Oct 19, 2026Partial shortageTemozolomide6 of 18 reported products affected · est. return Jul 31, 2026No current shortageBuffer Solution MelphalanDiscontinuedCarmustine0 of 1 reported products affected

All alkylatingagents shortage statuses →

Guides: what to do when your medication is in shortage · how to read shortage reports

Data reflects reports manufacturers are legally required to file with Health Canada, republished with per-drug aggregation by rxstat. Estimated end dates are supplied by manufacturers and frequently change. This page describes drug supply only and is not medical advice; never stop or switch a medication without speaking to your pharmacist or prescriber.