rxstatShortages › Busulfan

Busulfan (Myleran) shortage status

Partial shortage

Source: Health Canada shortage reports · Updated Jul 9, 2026

Some Busulfan products are in shortage in Canada (1 of 4 reported products), while others remain available. Your pharmacy may be able to substitute an unaffected manufacturer. The latest estimate for affected products to return is Oct 19, 2026.

A chemotherapy medication used to treat leukemia and prepare for bone marrow transplant.

Products affected
1 / 4
In shortage since
Jun 26, 2026
Est. full return
Oct 19, 2026
Reports on file
5
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Pharmacists can substitute an unaffected manufacturer's version, adjust strengths, and in most provinces adapt or renew a prescription on the spot.
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Shortage history

2023 2024 2025 2026

Shortage history (red bands = periods in shortage).

Reports by product

The DIN is printed on your prescription label.

Active shortage
PMS-BUSULFAN
6MG · SOLUTION · PHARMASCIENCE INC
DIN 02477343 · since Jun 26, 2026, est. end Oct 19, 2026 · Disruption of the manufacture of the drug.
Discontinued
BUSULFEX
60MG · SOLUTION · OTSUKA PHARMACEUTICAL CO LTD
DIN 02240602
Resolved
MYLERAN
2MG · TABLET · ASPEN PHARMACARE CANADA INC.
DIN 00004618 · ended Jan 22, 2020 · Delay in shipping of the drug.
Resolved
BUSULFAN FOR INJECTION
6MG · SOLUTION · STERIMAX INC
DIN 02463733 · ended Sep 5, 2019 · Delay in shipping of the drug.
Resolved
MYLERAN
2MG · TABLET · ASPEN PHARMACARE CANADA INC.
DIN 00004618 · ended Jul 24, 2018 · Demand increase for the drug.

What's happening

Busulfan is currently affected by an active shortage report filed with Health Canada by PHARMASCIENCE INC.

The reported cause is: disruption of the manufacture of the drug. Manufacturers must report shortages, but end-date estimates are their own projections and often move.

If your usual product is affected, a pharmacist is the fastest route to a solution: they can dispense an unaffected manufacturer's equivalent when one exists, and in most provinces can adapt doses or substitute a therapeutic alternative without a new appointment.

Busulfan is classified under “ALKYLATINGAGENTS” (ATC L01AB).

Recent changes

Common questions

What is Busulfan used for?

A chemotherapy medication used to treat leukemia and prepare for bone marrow transplant.

When will Busulfan be back in stock in Canada?

The latest manufacturer estimate is Oct 19, 2026. Estimates are self-reported and often slip; this page updates automatically when they change.

Why is Busulfan in shortage?

See the reports above; manufacturers must state a reason (most commonly manufacturing disruption or a surge in demand) when filing with Health Canada.

What can my pharmacist do about it?

Often quite a lot: substitute an equivalent product from an unaffected manufacturer, adjust quantities, or in most provinces adapt or renew prescriptions on the spot. Call your pharmacy before visiting, and call 811 for free health advice.

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Possible alternatives in the same class (alkylatingagents)

Drugs in the same therapeutic class, best-supplied first. These are not automatic substitutes: only your pharmacist or prescriber can judge whether a switch makes sense for you.

Guides: what to do when your medication is in shortage · how to read shortage reports

Data reflects reports manufacturers are legally required to file with Health Canada, republished with per-drug aggregation by rxstat. Estimated end dates are supplied by manufacturers and frequently change. This page describes drug supply only and is not medical advice; never stop or switch a medication without speaking to your pharmacist or prescriber.