rxstat › Classes › Alkylatingagents

Alkylatingagents: shortage status in Canada

5 of the 8 alkylatingagents rxstat tracks are currently in shortage in Canada, including 2 designated Tier 3 (most serious) by Health Canada. When one drug in a class is short, demand often shifts to its alternatives, so related drugs can tighten too; each page below shows which manufacturers are affected and the latest recovery estimates.
Widespread shortageCyclophosphamide4 of 10 reported products affected · est. return Jun 19, 2026Widespread shortageIfosfamide2 of 2 reported products affected · est. return Sep 30, 2026Partial shortageBendamustine2 of 8 reported products affected · est. return Jan 1, 2025Partial shortageBusulfan1 of 4 reported products affected · est. return Oct 19, 2026Partial shortageTemozolomide6 of 18 reported products affected · est. return Jul 31, 2026No current shortageBuffer Solution MelphalanDiscontinuedCarmustine0 of 1 reported products affectedDiscontinuedLomustine0 of 3 reported products affected

Guides: what to do when your medication is in shortage · how to read these statuses

Class groupings follow the WHO ATC classification in Health Canada's reports. Data reflects manufacturer mandatory filings; see methodology.