rxstat › Shortages › Sapropterin Dihydrochloride

Sapropterin Dihydrochloride (Kuvan) shortage status

Discontinued

Source: Health Canada shortage reports · Updated Jul 9, 2026

Sapropterin Dihydrochloride products have been discontinued in Canada. See the reports below for which products and when.

A medicine used to lower blood phenylalanine levels in phenylketonuria (PKU).

Products affected
0 / 1
Reports on file
2

Reports by product

The DIN is printed on your prescription label.

Discontinued
KUVAN
500MG · POWDER · BIOMARIN INTERNATIONAL LIMITED
DIN 02482215
Discontinued
KUVAN
500MG · POWDER · BIOMARIN INTERNATIONAL LIMITED
DIN 02482215

What's happening

One or more Sapropterin Dihydrochloride products have been permanently discontinued by their manufacturers. If your product is affected, ask your pharmacist about equivalent products still on the market.

Sapropterin Dihydrochloride is classified under “OTHER ALIMENTARY TRACT AND METABOLISM PRODUCTS” (ATC A16AX).

Recent changes

Common questions

What is Sapropterin Dihydrochloride used for?

A medicine used to lower blood phenylalanine levels in phenylketonuria (PKU).

When will Sapropterin Dihydrochloride be back in stock in Canada?

Manufacturers have not provided a reliable end date. This page updates automatically as soon as an estimate is filed.

Why is Sapropterin Dihydrochloride in shortage?

See the reports above; manufacturers must state a reason (most commonly manufacturing disruption or a surge in demand) when filing with Health Canada.

What can my pharmacist do about it?

Often quite a lot: substitute an equivalent product from an unaffected manufacturer, adjust quantities, or in most provinces adapt or renew prescriptions on the spot. Call your pharmacy before visiting, and call 811 for free health advice.

Email alerts

Get an email when this drug's status changes. Double opt-in, one-click unsubscribe.

Related drugs (other alimentary tract and metabolism products)

Avalglucosidase Alfa (Nexviazyme) Partial shortage 1 of 1 reported products affected · est. return Aug 25, 2026 Alglucosidase Alfa (Myozyme) Shortage anticipated 0 of 1 reported products affected Betaine (Cystadane) No current shortage Miglustat (Zavesca) No current shortage Nitisinone No current shortage Taliglucerase Alfa (Elelyso) Discontinued 0 of 1 reported products affected

Guides: what to do when your medication is in shortage · how to read shortage reports

Data reflects reports manufacturers are legally required to file with Health Canada, republished with per-drug aggregation by rxstat. Estimated end dates are supplied by manufacturers and frequently change. This page describes drug supply only and is not medical advice; never stop or switch a medication without speaking to your pharmacist or prescriber.