rxstat › Shortages › Methotrexate
Methotrexate shortage status
Partial shortage
Source: Health Canada shortage reports · Updated Jul 9, 2026
Some Methotrexate products are in shortage in Canada (3 of 31 reported products), while others remain available. Your pharmacy may be able to substitute an unaffected manufacturer. The latest estimate for affected products to return is Jun 30, 2023.
In shortage since
Dec 1, 2020
Est. full return
Jun 30, 2023
Talk to your pharmacist. Pharmacists can often substitute another manufacturer's version, a different strength, or (in most provinces) adapt or renew a prescription on the spot. Your free provincial health line is 811.
Reports by product
Active shortageNORDIMET
7.5MG · SOLUTION · NORDIC GROUP B.V.
DIN 02546531 · since Jun 2, 2025, no end estimate · Other (Please describe in comments)
Active shortageMETHOTREXATE TABLETS, USP
10MG · TABLET · PFIZER CANADA ULC
DIN 02182750 · since ?, no end estimate · Disruption of the manufacture of the drug.
Active shortageJAMP-METHOTREXATE
25MG · SOLUTION · JAMP PHARMA CORPORATION
DIN 02419173 · since Dec 1, 2020, est. end Jun 30, 2023 · Disruption of the manufacture of the drug.
AnticipatedNORDIMET
25MG · SOLUTION · NORDIC GROUP B.V.
DIN 02546612 · Other (Please describe in comments)
AnticipatedNORDIMET
15MG · SOLUTION · NORDIC GROUP B.V.
DIN 02546574 · Other (Please describe in comments)
AnticipatedNORDIMET
20MG · SOLUTION · NORDIC GROUP B.V.
DIN 02546590 · Other (Please describe in comments)
AnticipatedNORDIMET
10MG · SOLUTION · NORDIC GROUP B.V.
DIN 02546558 · Other (Please describe in comments)
ResolvedM-METHOTREXATE
2.5MG · TABLET · MANTRA PHARMA INC
DIN 02534916 · ended Mar 3, 2026 · Delay in shipping of the drug.
ResolvedACH-METHOTREXATE
2.5MG · TABLET · ACCORD HEALTHCARE INC
DIN 02509067 · ended Feb 13, 2026 · Disruption of the manufacture of the drug.
ResolvedM-METHOTREXATE
2.5MG · TABLET · MANTRA PHARMA INC
DIN 02534916 · ended Feb 2, 2026 · Delay in shipping of the drug.
ResolvedMETHOTREXATE INJECTION BP
25MG · SOLUTION · ACCORD HEALTHCARE INC
DIN 02327236 · ended Jan 30, 2026 · Requirements related to complying with good manufacturing practices.
ResolvedMETHOTREXATE INJECTION BP
25MG · SOLUTION · ACCORD HEALTHCARE INC
DIN 02474891 · ended Nov 15, 2024 · Requirements related to complying with good manufacturing practices.
Showing 12 of 60 reports. All reports are on file with Health Canada.
What's happening
Methotrexate is currently affected by 3 active shortage reports filed with Health Canada by NORDIC GROUP B.V., PFIZER CANADA ULC, JAMP PHARMA CORPORATION.
The reported causes are: other (please describe in comments); disruption of the manufacture of the drug. Manufacturers must report shortages, but end-date estimates are their own projections and often move.
If your usual product is affected, a pharmacist is the fastest route to a solution: they can dispense an unaffected manufacturer's equivalent when one exists, and in most provinces can adapt doses or substitute a therapeutic alternative without a new appointment.
Methotrexate is classified under “ANTIMETABOLITES” (ATC L01BA).
Recent changes
Common questions
When will Methotrexate be back in stock in Canada?
The latest manufacturer estimate is Jun 30, 2023. Estimates are self-reported and often slip; this page updates automatically when they change.
Why is Methotrexate in shortage?
See the reports above; manufacturers must state a reason (most commonly manufacturing disruption or a surge in demand) when filing with Health Canada.
What can my pharmacist do about it?
Often quite a lot: substitute an equivalent product from an unaffected manufacturer, adjust quantities, or in most provinces adapt or renew prescriptions on the spot. Call your pharmacy before visiting, and call 811 for free health advice.
Guides: what to do when your medication is in shortage · how to read shortage reports
Data reflects reports manufacturers are legally required to file with Health Canada, republished with per-drug aggregation by rxstat. Estimated end dates are supplied by manufacturers and frequently change. This page describes drug supply only and is not medical advice; never stop or switch a medication without speaking to your pharmacist or prescriber.