Source: Health Canada shortage reports · Updated Jul 9, 2026
Some Methotrexate products are in shortage in Canada (3 of 31 reported products), while others remain available. Your pharmacy may be able to substitute an unaffected manufacturer.
A medication used to treat certain cancers and autoimmune conditions such as rheumatoid arthritis and psoriasis.
Products affected
3 / 31
In shortage since
Dec 1, 2020
Reports on file
95
Talk to a pharmacist
Pharmacists can substitute an unaffected manufacturer's version, adjust strengths, and in most provinces adapt or renew a prescription on the spot.
Independent services, not affiliated with rxstat; referral fees may apply. Free options exist depending on your province. In an emergency call 911; free health advice at 811.
Shortage history
Shortage history (red bands = periods in shortage).
Reports by product
The DIN is printed on your prescription label.
Active shortage
NORDIMET
7.5MG · SOLUTION · NORDIC GROUP B.V.
DIN 02546531 · since Jun 2, 2025, no end estimate · This strength of the product is not currently available in Canada. The status of this presentation may be re-evaluated in the future based on various factors.
Active shortage
METHOTREXATE TABLETS, USP
10MG · TABLET · PFIZER CANADA ULC
DIN 02182750 · since ?, no end estimate · Disruption of the manufacture of the drug.
Active shortage
JAMP-METHOTREXATE
25MG · SOLUTION · JAMP PHARMA CORPORATION
DIN 02419173 · since Dec 1, 2020, est. end Jun 30, 2023 · Disruption of the manufacture of the drug.
Anticipated
NORDIMET
25MG · SOLUTION · NORDIC GROUP B.V.
DIN 02546612 · This strength of the product is not currently available in Canada. The status of this presentation may be re-evaluated in the future based on various factors.
Anticipated
NORDIMET
15MG · SOLUTION · NORDIC GROUP B.V.
DIN 02546574 · This strength of the product is not currently available in Canada. The status of this presentation may be re-evaluated in the future based on various factors.
Anticipated
NORDIMET
20MG · SOLUTION · NORDIC GROUP B.V.
DIN 02546590 · This strength of the product is not currently available in Canada. The status of this presentation may be re-evaluated in the future based on various factors.
Anticipated
NORDIMET
10MG · SOLUTION · NORDIC GROUP B.V.
DIN 02546558 · This strength of the product is not currently available in Canada. The status of this presentation may be re-evaluated in the future based on various factors.
Resolved
M-METHOTREXATE
2.5MG · TABLET · MANTRA PHARMA INC
DIN 02534916 · ended Mar 3, 2026 · Delay in shipping of the drug.
Resolved
ACH-METHOTREXATE
2.5MG · TABLET · ACCORD HEALTHCARE INC
DIN 02509067 · ended Feb 13, 2026 · Disruption of the manufacture of the drug.
Resolved
M-METHOTREXATE
2.5MG · TABLET · MANTRA PHARMA INC
DIN 02534916 · ended Feb 2, 2026 · Delay in shipping of the drug.
Resolved
METHOTREXATE INJECTION BP
25MG · SOLUTION · ACCORD HEALTHCARE INC
DIN 02327236 · ended Jan 30, 2026 · Requirements related to complying with good manufacturing practices.
Resolved
METHOTREXATE INJECTION BP
25MG · SOLUTION · ACCORD HEALTHCARE INC
DIN 02474891 · ended Nov 15, 2024 · Requirements related to complying with good manufacturing practices.
Showing 12 of 60 reports. All reports are on file with Health Canada.
What's happening
Methotrexate is currently affected by 3 active shortage reports filed with Health Canada by NORDIC GROUP B.V., PFIZER CANADA ULC, JAMP PHARMA CORPORATION.
The reported causes are: this strength of the product is not currently available in canada. the status of this presentation may be re-evaluated in the future based on various factors; disruption of the manufacture of the drug. Manufacturers must report shortages, but end-date estimates are their own projections and often move.
If your usual product is affected, a pharmacist is the fastest route to a solution: they can dispense an unaffected manufacturer's equivalent when one exists, and in most provinces can adapt doses or substitute a therapeutic alternative without a new appointment.
Methotrexate is classified under “ANTIMETABOLITES” (ATC L01BA).
Recent changes
No changes recorded yet.
Common questions
What is Methotrexate used for?
A medication used to treat certain cancers and autoimmune conditions such as rheumatoid arthritis and psoriasis.
When will Methotrexate be back in stock in Canada?
Manufacturers have not provided a reliable end date. This page updates automatically as soon as an estimate is filed.
Why is Methotrexate in shortage?
See the reports above; manufacturers must state a reason (most commonly manufacturing disruption or a surge in demand) when filing with Health Canada.
What can my pharmacist do about it?
Often quite a lot: substitute an equivalent product from an unaffected manufacturer, adjust quantities, or in most provinces adapt or renew prescriptions on the spot. Call your pharmacy before visiting, and call 811 for free health advice.
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Drugs in the same therapeutic class, best-supplied first. These are not automatic substitutes: only your pharmacist or prescriber can judge whether a switch makes sense for you.
Data reflects reports manufacturers are legally required to file with Health Canada, republished with per-drug aggregation by rxstat. Estimated end dates are supplied by manufacturers and frequently change. This page describes drug supply only and is not medical advice; never stop or switch a medication without speaking to your pharmacist or prescriber.