rxstatShortages › Fluorouracil

Fluorouracil (Efudex) shortage status

No current shortage

Source: Health Canada shortage reports · Updated Jul 9, 2026

Fluorouracil has no current shortage reported in Canada. It has been in shortage before; the history is below.

A chemotherapy drug used to treat several cancers and, as a cream, certain precancerous skin lesions.

Products affected
0 / 3
Reports on file
14

Shortage history

2023 2024 2025 2026

Shortage history (red bands = periods in shortage).

Reports by product

The DIN is printed on your prescription label.

Avoided
EFUDEX
5% · CREAM · BAUSCH HEALTH, CANADA INC.
DIN 00330582 · ended Oct 15, 2025 · Delay in shipping of the drug.
Resolved
EFUDEX
5% · CREAM · BAUSCH HEALTH, CANADA INC.
DIN 00330582 · ended Jul 18, 2025 · Limited availability – product on allocation. Reason: interruption in manufacturing.
Resolved
EFUDEX
5% · CREAM · BAUSCH HEALTH, CANADA INC.
DIN 00330582 · ended Jun 25, 2025 · Shortage of an active ingredient.
Resolved
EFUDEX
5% · CREAM · BAUSCH HEALTH, CANADA INC.
DIN 00330582 · ended May 21, 2024 · Demand increase for the drug.
Resolved
EFUDEX
5% · CREAM · BAUSCH HEALTH, CANADA INC.
DIN 00330582 · ended Apr 16, 2024 · Change in KSM (key starting material) in drug substance requiring SNDS filing
Resolved
EFUDEX
5% · CREAM · BAUSCH HEALTH, CANADA INC.
DIN 00330582 · ended Nov 6, 2023 · Capacity Problem in Production
Resolved
FLUOROURACIL INJECTION USP
50MG · SOLUTION · ACCORD HEALTHCARE INC
DIN 02413450 · ended Mar 28, 2022 · Delay in shipping of the drug.
Discontinued
FLUOROURACIL INJECTION USP
50MG · SOLUTION · PFIZER CANADA ULC
DIN 02182742
Resolved
EFUDEX
5% · CREAM · VALEANT CANADA LP/VALEANT CANADA S.E.C.
DIN 00330582 · ended Apr 28, 2020 · delay in production
Resolved
EFUDEX CRM 5%
5% · CREAM · VALEANT CANADA LP/VALEANT CANADA S.E.C.
DIN 00330582 · ended Jul 30, 2019 · delay cmo
Resolved
EFUDEX CRM 5%
5% · CREAM · VALEANT CANADA LP/VALEANT CANADA S.E.C.
DIN 00330582 · ended Aug 6, 2018
Resolved
FLUOROURACIL INJECTION
5G · SOLUTION · ACCORD HEALTHCARE INC
DIN 02413450 · ended Jul 7, 2017 · Lots under investigation

Showing 12 of 14 reports. All reports are on file with Health Canada.

What's happening

There are no active shortage reports for Fluorouracil. Health Canada has 14 historical reports on file for this drug, so supply has been disrupted before; the change log below shows the history.

Fluorouracil is classified under “ANTIMETABOLITES” (ATC L01BC).

Recent changes

Common questions

What is Fluorouracil used for?

A chemotherapy drug used to treat several cancers and, as a cream, certain precancerous skin lesions.

When will Fluorouracil be back in stock in Canada?

Fluorouracil has no active shortage; supply is normal per Health Canada reports.

Why is Fluorouracil in shortage?

It isn't currently. Past reports and their reasons are listed above.

What can my pharmacist do about it?

Often quite a lot: substitute an equivalent product from an unaffected manufacturer, adjust quantities, or in most provinces adapt or renew prescriptions on the spot. Call your pharmacy before visiting, and call 811 for free health advice.

Email alerts

Get an email when this drug's status changes. Double opt-in, one-click unsubscribe.

Related drugs (antimetabolites)

Guides: what to do when your medication is in shortage · how to read shortage reports

Data reflects reports manufacturers are legally required to file with Health Canada, republished with per-drug aggregation by rxstat. Estimated end dates are supplied by manufacturers and frequently change. This page describes drug supply only and is not medical advice; never stop or switch a medication without speaking to your pharmacist or prescriber.