Source: Health Canada shortage reports · Updated Jul 9, 2026
Some Loxapine products are in shortage in Canada (4 of 10 reported products), while others remain available. Your pharmacy may be able to substitute an unaffected manufacturer.
An antipsychotic used to treat schizophrenia and other psychotic disorders.
Products affected
4 / 10
In shortage since
Mar 10, 2017
Reports on file
18
Talk to a pharmacist
Pharmacists can substitute an unaffected manufacturer's version, adjust strengths, and in most provinces adapt or renew a prescription on the spot.
Independent services, not affiliated with rxstat; referral fees may apply. Free options exist depending on your province. In an emergency call 911; free health advice at 811.
Shortage history
Shortage history (red bands = periods in shortage).
Reports by product
The DIN is printed on your prescription label.
Active shortage
APO-LOXAPINE
5MG · TABLET · APOTEX INC
DIN 02237651 · since Mar 10, 2017, no end estimate · Disruption of the manufacture of the drug.
Active shortage
APO-LOXAPINE
10MG · TABLET · APOTEX INC
DIN 02237652 · since Mar 10, 2017, no end estimate · Disruption of the manufacture of the drug.
Active shortage
APO-LOXAPINE
25MG · TABLET · APOTEX INC
DIN 02237653 · since Mar 10, 2017, no end estimate · Disruption of the manufacture of the drug.
Active shortage
APO-LOXAPINE
50MG · TABLET · APOTEX INC
DIN 02237654 · since Mar 10, 2017, no end estimate · Disruption of the manufacture of the drug.
Resolved
XYLAC
50MG · TABLET · PENDOPHARM DIVISION OF DE PHARMASCIENCE INC
DIN 02230840 · ended Sep 21, 2018 · Disruption of the manufacture of the drug.
Resolved
XYLAC
5MG · TABLET · PENDOPHARM DIVISION OF DE PHARMASCIENCE INC
DIN 02230837 · ended Sep 18, 2018 · Disruption of the manufacture of the drug.
DIN 02169991 · ended Sep 16, 2024 · Demand increase for the drug.
Resolved
XYLAC
2.5MG · TABLET · PENDOPHARM DIVISION OF PHARMASCIENCE INC
DIN 02242868 · ended May 9, 2024 · Disruption of the manufacture of the drug.
Showing 12 of 18 reports. All reports are on file with Health Canada.
What's happening
Loxapine is currently affected by 4 active shortage reports filed with Health Canada by APOTEX INC.
The reported cause is: disruption of the manufacture of the drug. Manufacturers must report shortages, but end-date estimates are their own projections and often move.
If your usual product is affected, a pharmacist is the fastest route to a solution: they can dispense an unaffected manufacturer's equivalent when one exists, and in most provinces can adapt doses or substitute a therapeutic alternative without a new appointment.
Loxapine is classified under “ANTIPSYCHOTICS” (ATC N05AH).
Recent changes
No changes recorded yet.
Common questions
What is Loxapine used for?
An antipsychotic used to treat schizophrenia and other psychotic disorders.
When will Loxapine be back in stock in Canada?
Manufacturers have not provided a reliable end date. This page updates automatically as soon as an estimate is filed.
Why is Loxapine in shortage?
See the reports above; manufacturers must state a reason (most commonly manufacturing disruption or a surge in demand) when filing with Health Canada.
What can my pharmacist do about it?
Often quite a lot: substitute an equivalent product from an unaffected manufacturer, adjust quantities, or in most provinces adapt or renew prescriptions on the spot. Call your pharmacy before visiting, and call 811 for free health advice.
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Possible alternatives in the same class (antipsychotics)
Drugs in the same therapeutic class, best-supplied first. These are not automatic substitutes: only your pharmacist or prescriber can judge whether a switch makes sense for you.
Data reflects reports manufacturers are legally required to file with Health Canada, republished with per-drug aggregation by rxstat. Estimated end dates are supplied by manufacturers and frequently change. This page describes drug supply only and is not medical advice; never stop or switch a medication without speaking to your pharmacist or prescriber.