Methotrimeprazine (Methoprazine, Nozinan) shortage status
Partial shortage
Source: Health Canada shortage reports · Updated Aug 13, 2026
Some Methotrimeprazine products are in shortage in Canada (1 of 5 reported products), while others remain available. Your pharmacy may be able to substitute an unaffected manufacturer. The latest estimate for affected products to return is Sep 18, 2026.
A phenothiazine used to treat severe pain, agitation, and psychosis, often in palliative care.
Products affected
1 / 5
In shortage since
Aug 11, 2026
Est. full return
Sep 18, 2026
Reports on file
15
Talk to a pharmacist
Pharmacists can substitute an unaffected manufacturer's version, adjust strengths, and in most provinces adapt or renew a prescription on the spot.
Independent services, not affiliated with rxstat; referral fees may apply. Free options exist depending on your province. In an emergency call 911; free health advice at 811.
Shortage history
Shortage history (red bands = periods in shortage).
Reports by product
The DIN is printed on your prescription label.
Active shortage
METHOPRAZINE
50MG · TABLET · AA PHARMA INC
DIN 02238406 · since Aug 11, 2026, est. end Sep 18, 2026 · Disruption of the manufacture of the drug.
Resolved
METHOPRAZINE
5MG · TABLET · AA PHARMA INC
DIN 02238404 · ended Jul 21, 2026 · Disruption of the manufacture of the drug.
Resolved
METHOPRAZINE
5MG · TABLET · AA PHARMA INC
DIN 02238404 · ended Mar 11, 2025 · Disruption of the manufacture of the drug.
Resolved
METHOPRAZINE
25MG · TABLET · AA PHARMA INC
DIN 02238405 · ended Dec 18, 2024 · Disruption of the manufacture of the drug.
Resolved
NOZINAN
25MG · SOLUTION · SANOFI-AVENTIS CANADA INC
DIN 01927698 · ended Sep 29, 2023 · The product will continue to be on allocation.
Resolved
NOZINAN INJ 25MG/ML
25MG · SOLUTION · SANOFI-AVENTIS CANADA INC
DIN 01927698 · ended May 13, 2022
Resolved
METHOPRAZINE
5MG · TABLET · AA PHARMA INC
DIN 02238404 · ended Mar 15, 2023 · Disruption of the manufacture of the drug.
Resolved
METHOPRAZINE
2MG · TABLET · AA PHARMA INC
DIN 02238403 · ended Mar 15, 2023 · Disruption of the manufacture of the drug.
Resolved
NOZINAN INJ 25MG/ML
25MG · SOLUTION · SANOFI-AVENTIS CANADA INC
DIN 01927698 · ended Dec 15, 2022
Resolved
METHOPRAZINE
25MG · TABLET · AA PHARMA INC
DIN 02238405 · ended Aug 31, 2021 · Disruption of the manufacture of the drug.
Avoided
NOZINAN INJ 25MG/ML
25MG · SOLUTION · SANOFI-AVENTIS CANADA INC
DIN 01927698 · ended Aug 7, 2020
Resolved
NOZINAN INJ 25MG/ML
25MG · SOLUTION · SANOFI-AVENTIS CANADA INC
DIN 01927698 · ended May 4, 2020
Showing 12 of 15 reports. All reports are on file with Health Canada.
What's happening
Methotrimeprazine is currently affected by an active shortage report filed with Health Canada by AA PHARMA INC.
The reported cause is: disruption of the manufacture of the drug. Manufacturers must report shortages, but end-date estimates are their own projections and often move.
If your usual product is affected, a pharmacist is the fastest route to a solution: they can dispense an unaffected manufacturer's equivalent when one exists, and in most provinces can adapt doses or substitute a therapeutic alternative without a new appointment.
Methotrimeprazine is classified under “ANTIPSYCHOTICS” (ATC N05AA).
Recent changes
Aug 13, 2026
New report filed
Jul 23, 2026
Shortage resolved
Jul 16, 2026
Estimated end date pushed back : Jul 17, 2026 → Jul 24, 2026
Common questions
What is Methotrimeprazine used for?
A phenothiazine used to treat severe pain, agitation, and psychosis, often in palliative care.
When will Methotrimeprazine be back in stock in Canada?
The latest manufacturer estimate is Sep 18, 2026. Estimates are self-reported and often slip; this page updates automatically when they change.
Why is Methotrimeprazine in shortage?
See the reports above; manufacturers must state a reason (most commonly manufacturing disruption or a surge in demand) when filing with Health Canada.
What can my pharmacist do about it?
Often quite a lot: substitute an equivalent product from an unaffected manufacturer, adjust quantities, or in most provinces adapt or renew prescriptions on the spot. Call your pharmacy before visiting, and call 811 for free health advice.
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Possible alternatives in the same class (antipsychotics)
Drugs in the same therapeutic class, best-supplied first. These are not automatic substitutes: only your pharmacist or prescriber can judge whether a switch makes sense for you.
Data reflects reports manufacturers are legally required to file with Health Canada, republished with per-drug aggregation by rxstat. Estimated end dates are supplied by manufacturers and frequently change. This page describes drug supply only and is not medical advice; never stop or switch a medication without speaking to your pharmacist or prescriber.