rxstatShortages › Hydrochlorothiazide Losartan

Hydrochlorothiazide Losartan (Hyzaar, Hyzaar Ds) shortage status

Partial shortage

Source: Health Canada shortage reports · Updated Jul 9, 2026

Some Hydrochlorothiazide Losartan products are in shortage in Canada (3 of 35 reported products), while others remain available. Your pharmacy may be able to substitute an unaffected manufacturer.

A combination of a blood pressure medication and a water pill used to treat high blood pressure.

Products affected
3 / 35
In shortage since
Oct 13, 2021
Reports on file
167
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Shortage history

2023 2024 2025 2026

Shortage history (red bands = periods in shortage).

Reports by product

The DIN is printed on your prescription label.

Active shortage
PMS-LOSARTAN-HCTZ
12.5MG 100MG · TABLET · PHARMASCIENCE INC
DIN 02392232 · since Feb 5, 2026, est. end Jul 7, 2026 · Disruption of the manufacture of the drug.
Active shortage
LOSARTAN HCT
12.5MG 100MG · TABLET · SIVEM PHARMACEUTICALS ULC
DIN 02388979 · since Oct 13, 2021, no end estimate · Requirements related to complying with good manufacturing practices.
Active shortage
LOSARTAN HCT
12.5MG 100MG · TABLET · SIVEM PHARMACEUTICALS ULC
DIN 02388979 · since Oct 13, 2021, no end estimate · Requirements related to complying with good manufacturing practices.
Active shortage
LOSARTAN HCT
12.5MG 50MG · TABLET · SIVEM PHARMACEUTICALS ULC
DIN 02388960 · since Oct 13, 2021, no end estimate · Requirements related to complying with good manufacturing practices.
Active shortage
LOSARTAN HCT
12.5MG 50MG · TABLET · SIVEM PHARMACEUTICALS ULC
DIN 02388960 · since Oct 13, 2021, no end estimate · Requirements related to complying with good manufacturing practices.
Resolved
SANDOZ LOSARTAN HCT
12.5MG 100MG · TABLET · SANDOZ CANADA INCORPORATED
DIN 02362449 · ended Jun 29, 2026 · Demand increase for the drug.
Resolved
SANDOZ LOSARTAN HCT
50MG 12.5MG · TABLET · SANDOZ CANADA INCORPORATED
DIN 02313375 · ended Jun 22, 2026 · Demand increase for the drug.
Resolved
PMS-LOSARTAN-HCTZ
12.5MG 50MG · TABLET · PHARMASCIENCE INC
DIN 02392224 · ended May 4, 2026 · Disruption of the manufacture of the drug.
Resolved
LOSARTAN HCT DS
25MG 100MG · TABLET · SIVEM PHARMACEUTICALS ULC
DIN 02388987 · ended Oct 21, 2025 · Requirements related to complying with good manufacturing practices.
Resolved
LOSARTAN HCT DS
25MG 100MG · TABLET · SIVEM PHARMACEUTICALS ULC
DIN 02388987 · ended Oct 21, 2025 · Requirements related to complying with good manufacturing practices.
Resolved
LOSARTAN/HCTZ
50MG 12.5MG · TABLET · SANIS HEALTH INC
DIN 02427648 · ended Sep 11, 2025 · Disruption of the manufacture of the drug.
Resolved
SANDOZ LOSARTAN HCT
12.5MG 100MG · TABLET · SANDOZ CANADA INCORPORATED
DIN 02362449 · ended May 12, 2025 · Disruption of the manufacture of the drug.

Showing 12 of 60 reports. All reports are on file with Health Canada.

What's happening

Hydrochlorothiazide Losartan is currently affected by 3 active shortage reports filed with Health Canada by PHARMASCIENCE INC, SIVEM PHARMACEUTICALS ULC.

The reported causes are: disruption of the manufacture of the drug; requirements related to complying with good manufacturing practices. Manufacturers must report shortages, but end-date estimates are their own projections and often move.

If your usual product is affected, a pharmacist is the fastest route to a solution: they can dispense an unaffected manufacturer's equivalent when one exists, and in most provinces can adapt doses or substitute a therapeutic alternative without a new appointment.

Hydrochlorothiazide Losartan is classified under “ANGIOTENSIN II ANTAGONISTS, COMBINATIONS” (ATC C09DA).

Recent changes

Common questions

What is Hydrochlorothiazide Losartan used for?

A combination of a blood pressure medication and a water pill used to treat high blood pressure.

When will Hydrochlorothiazide Losartan be back in stock in Canada?

Manufacturers have not provided a reliable end date. This page updates automatically as soon as an estimate is filed.

Why is Hydrochlorothiazide Losartan in shortage?

See the reports above; manufacturers must state a reason (most commonly manufacturing disruption or a surge in demand) when filing with Health Canada.

What can my pharmacist do about it?

Often quite a lot: substitute an equivalent product from an unaffected manufacturer, adjust quantities, or in most provinces adapt or renew prescriptions on the spot. Call your pharmacy before visiting, and call 811 for free health advice.

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Possible alternatives in the same class (angiotensin ii antagonists, combinations)

Drugs in the same therapeutic class, best-supplied first. These are not automatic substitutes: only your pharmacist or prescriber can judge whether a switch makes sense for you.

Guides: what to do when your medication is in shortage · how to read shortage reports

Data reflects reports manufacturers are legally required to file with Health Canada, republished with per-drug aggregation by rxstat. Estimated end dates are supplied by manufacturers and frequently change. This page describes drug supply only and is not medical advice; never stop or switch a medication without speaking to your pharmacist or prescriber.