Irbesartan Hydrochlorothiazide (Avalide) shortage status
Partial shortage
Source: Health Canada shortage reports · Updated Jul 28, 2026
Some Irbesartan Hydrochlorothiazide products are in shortage in Canada (14 of 35 reported products), while others remain available. Your pharmacy may be able to substitute an unaffected manufacturer. The latest estimate for affected products to return is Mar 3, 2027.
A combination of a blood pressure medication and a water pill used to treat high blood pressure.
Products affected
14 / 35
In shortage since
Sep 17, 2018
Est. full return
Mar 3, 2027
Reports on file
147
Talk to a pharmacist
Pharmacists can substitute an unaffected manufacturer's version, adjust strengths, and in most provinces adapt or renew a prescription on the spot.
Independent services, not affiliated with rxstat; referral fees may apply. Free options exist depending on your province. In an emergency call 911; free health advice at 811.
Shortage history
Shortage history (red bands = periods in shortage).
Reports by product
The DIN is printed on your prescription label.
Active shortage
SANDOZ IRBESARTAN HCT
25MG
300MG · TABLET · SANDOZ CANADA INCORPORATED
DIN 02337444 · since Jul 27, 2026, est. end Nov 27, 2026 · Disruption of the manufacture of the drug.
Active shortage
PMS-IRBESARTAN-HCTZ
150MG
12.5MG · TABLET · PHARMASCIENCE INC
DIN 02328518 · since Jul 21, 2026, est. end Mar 3, 2027 · Disruption of the manufacture of the drug.
DIN 02337428 · since Apr 6, 2026, est. end Sep 18, 2026 · Disruption of the manufacture of the drug.
Active shortage
PMS-IRBESARTAN-HCTZ
12.5MG
300MG · TABLET · PHARMASCIENCE INC
DIN 02328526 · since Nov 14, 2022, est. end Dec 1, 2026 · Disruption of the manufacture of the drug.
Active shortage
IRBESARTAN/HCTZ
12.5MG
150MG · TABLET · SANIS HEALTH INC
DIN 02372886 · since Nov 18, 2024, no end estimate · Disruption of the manufacture of the drug.
Active shortage
IRBESARTAN/HCTZ
12.5MG
300MG · TABLET · SANIS HEALTH INC
DIN 02372894 · since Oct 7, 2024, no end estimate · Disruption of the manufacture of the drug.
Active shortage
IRBESARTAN/HCTZ
25MG
300MG · TABLET · SANIS HEALTH INC
DIN 02372908 · since Jun 1, 2024, no end estimate · Disruption of the manufacture of the drug.
Active shortage
TEVA-IRBESARTAN HCTZ
300MG
25MG · TABLET · TEVA CANADA LIMITED
DIN 02330539 · since Mar 10, 2024, no end estimate · Disruption of the manufacture of the drug.
Active shortage
JAMP-IRBESARTAN AND HYDROCHLOROTHIAZIDE
150MG
12.5MG · TABLET · JAMP PHARMA CORPORATION
DIN 02418223 · since Oct 7, 2019, est. end Dec 30, 2022 · Disruption of the manufacture of the drug.
Active shortage
JAMP-IRBESARTAN AND HYDROCHLOROTHIAZIDE
25MG
300MG · TABLET · JAMP PHARMA CORPORATION
DIN 02418258 · since Oct 7, 2019, est. end Dec 30, 2022 · Disruption of the manufacture of the drug.
Showing 12 of 60 reports. All reports are on file with Health Canada.
What's happening
Irbesartan Hydrochlorothiazide is currently affected by 14 active shortage reports filed with Health Canada by SANDOZ CANADA INCORPORATED, PHARMASCIENCE INC, SANIS HEALTH INC, TEVA CANADA LIMITED and 2 others.
The reported causes are: disruption of the manufacture of the drug; demand increase for the drug; shortage of an active ingredient; requirements related to complying with good manufacturing practices. Manufacturers must report shortages, but end-date estimates are their own projections and often move.
If your usual product is affected, a pharmacist is the fastest route to a solution: they can dispense an unaffected manufacturer's equivalent when one exists, and in most provinces can adapt doses or substitute a therapeutic alternative without a new appointment.
Irbesartan Hydrochlorothiazide is classified under “ANGIOTENSIN II ANTAGONISTS, COMBINATIONS” (ATC C09DA).
Recent changes
Jul 28, 2026
New report filed
Jul 22, 2026
New report filed
Jul 22, 2026
Status changed
Jul 22, 2026
Estimated end date pushed back : Feb 28, 2027 → Mar 3, 2027
Jul 13, 2026
Estimated end date moved earlier : Dec 4, 2026 → Nov 6, 2026
Jul 9, 2026
New report filed
Common questions
What is Irbesartan Hydrochlorothiazide used for?
A combination of a blood pressure medication and a water pill used to treat high blood pressure.
When will Irbesartan Hydrochlorothiazide be back in stock in Canada?
The latest manufacturer estimate is Mar 3, 2027. Estimates are self-reported and often slip; this page updates automatically when they change.
Why is Irbesartan Hydrochlorothiazide in shortage?
See the reports above; manufacturers must state a reason (most commonly manufacturing disruption or a surge in demand) when filing with Health Canada.
What can my pharmacist do about it?
Often quite a lot: substitute an equivalent product from an unaffected manufacturer, adjust quantities, or in most provinces adapt or renew prescriptions on the spot. Call your pharmacy before visiting, and call 811 for free health advice.
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Drugs in the same therapeutic class, best-supplied first. These are not automatic substitutes: only your pharmacist or prescriber can judge whether a switch makes sense for you.
Data reflects reports manufacturers are legally required to file with Health Canada, republished with per-drug aggregation by rxstat. Estimated end dates are supplied by manufacturers and frequently change. This page describes drug supply only and is not medical advice; never stop or switch a medication without speaking to your pharmacist or prescriber.