rxstat › Shortages › Estradiol
Estradiol shortage status
Partial shortage
Source: Health Canada shortage reports · Updated Jul 9, 2026
Some Estradiol products are in shortage in Canada (6 of 24 reported products), while others remain available. Your pharmacy may be able to substitute an unaffected manufacturer. The latest estimate for affected products to return is Aug 20, 2026.
In shortage since
Jul 1, 2019
Est. full return
Aug 20, 2026
Talk to your pharmacist. Pharmacists can often substitute another manufacturer's version, a different strength, or (in most provinces) adapt or renew a prescription on the spot. Your free provincial health line is 811.
Reports by product
Active shortageCLIMARA 50
50MCG · PATCH · BAYER INC
DIN 02231509 · since Jun 15, 2026, est. end Jul 24, 2026 · Demand increase for the drug.
Active shortageCLIMARA 75
75MCG · PATCH · BAYER INC
DIN 02247500 · since Jun 15, 2026, est. end Jul 24, 2026 · Demand increase for the drug.
Active shortageCLIMARA 25
25MCG · PATCH · BAYER INC
DIN 02247499 · since Jun 15, 2026, est. end Aug 20, 2026 · Demand increase for the drug.
Active shortageESTRACE
2MG · TABLET · ACERUS PHARMACEUTICALS CORPORATION
DIN 02148595 · since Jul 1, 2019, no end estimate · Disruption of the manufacture of the drug.
Active shortageESTRACE
1MG · TABLET · ACERUS PHARMACEUTICALS CORPORATION
DIN 02148587 · since Jul 1, 2019, no end estimate · Disruption of the manufacture of the drug.
Active shortageESTRACE
0.5MG · TABLET · ACERUS PHARMACEUTICALS CORPORATION
DIN 02225190 · since Jul 1, 2019, no end estimate · Disruption of the manufacture of the drug.
ResolvedESTRADOT 75
75MCG · PATCH · SANDOZ CANADA INCORPORATED
DIN 02244001 · ended Jun 8, 2026 · Disruption of the manufacture of the drug.
ResolvedSANDOZ ESTRADIOL DERM 75
75MCG · PATCH · SANDOZ CANADA INCORPORATED
DIN 02246968 · ended Jun 15, 2026 · Demand increase for the drug.
ResolvedESTRADOT 25
25MCG · PATCH · SANDOZ CANADA INCORPORATED
DIN 02245676 · ended Jun 8, 2026 · Disruption of the manufacture of the drug.
ResolvedLUPIN-ESTRADIOL
0.5MG · TABLET · LUPIN PHARMA CANADA LIMITED
DIN 02449048 · ended Jun 5, 2026 · Disruption of the manufacture of the drug.
ResolvedLUPIN-ESTRADIOL
1MG · TABLET · LUPIN PHARMA CANADA LIMITED
DIN 02449056 · ended Jun 8, 2026 · Disruption of the manufacture of the drug.
ResolvedLUPIN-ESTRADIOL
2MG · TABLET · LUPIN PHARMA CANADA LIMITED
DIN 02449064 · ended Jun 3, 2026 · Disruption of the manufacture of the drug.
Showing 12 of 60 reports. All reports are on file with Health Canada.
What's happening
Estradiol is currently affected by 6 active shortage reports filed with Health Canada by BAYER INC, ACERUS PHARMACEUTICALS CORPORATION.
The reported causes are: demand increase for the drug; disruption of the manufacture of the drug. Manufacturers must report shortages, but end-date estimates are their own projections and often move.
If your usual product is affected, a pharmacist is the fastest route to a solution: they can dispense an unaffected manufacturer's equivalent when one exists, and in most provinces can adapt doses or substitute a therapeutic alternative without a new appointment.
Estradiol is classified under “ESTROGENS” (ATC G03CA).
Recent changes
Common questions
When will Estradiol be back in stock in Canada?
The latest manufacturer estimate is Aug 20, 2026. Estimates are self-reported and often slip; this page updates automatically when they change.
Why is Estradiol in shortage?
See the reports above; manufacturers must state a reason (most commonly manufacturing disruption or a surge in demand) when filing with Health Canada.
What can my pharmacist do about it?
Often quite a lot: substitute an equivalent product from an unaffected manufacturer, adjust quantities, or in most provinces adapt or renew prescriptions on the spot. Call your pharmacy before visiting, and call 811 for free health advice.
Guides: what to do when your medication is in shortage · how to read shortage reports
Data reflects reports manufacturers are legally required to file with Health Canada, republished with per-drug aggregation by rxstat. Estimated end dates are supplied by manufacturers and frequently change. This page describes drug supply only and is not medical advice; never stop or switch a medication without speaking to your pharmacist or prescriber.