Conjugated Estrogens (Premarin, Premarin Intravenous) shortage status
Partial shortage
Source: Health Canada shortage reports · Updated Aug 18, 2026
Some Conjugated Estrogens products are in shortage in Canada (1 of 4 reported products), while others remain available. Your pharmacy may be able to substitute an unaffected manufacturer.
An estrogen hormone therapy used to relieve menopausal symptoms.
Products affected
1 / 4
In shortage since
Jun 30, 2026
Reports on file
13
Talk to a pharmacist
Pharmacists can substitute an unaffected manufacturer's version, adjust strengths, and in most provinces adapt or renew a prescription on the spot.
Independent services, not affiliated with rxstat; referral fees may apply. Free options exist depending on your province. In an emergency call 911; free health advice at 811.
Shortage history
Shortage history (red bands = periods in shortage).
Reports by product
The DIN is printed on your prescription label.
Active shortage
PREMARIN VAGINAL CREAM
0.625MG · CREAM · PFIZER CANADA ULC
DIN 02043440 · since Jun 30, 2026, no end estimate · Disruption of the manufacture of the drug.
Resolved
PREMARIN VAGINAL CREAM
0.625MG · CREAM · PFIZER CANADA ULC
DIN 02043440 · ended Feb 21, 2026 · Disruption of the manufacture of the drug.
Resolved
PREMARIN VAGINAL CREAM
0.625MG · CREAM · PFIZER CANADA ULC
DIN 02043440 · ended Oct 7, 2025 · Disruption of the manufacture of the drug.
Resolved
PREMARIN VAGINAL CREAM
0.625MG · CREAM · PFIZER CANADA ULC
DIN 02043440 · ended Apr 11, 2025 · Disruption of the manufacture of the drug.
DIN 02414694 · ended Jul 11, 2024 · Demand increase for the drug.
Resolved
PREMARIN INTRAVENOUS
25MG · POWDER FOR SOLUTION · PFIZER CANADA ULC
DIN 02043386 · ended Jun 1, 2023 · Demand increase for the drug.
Resolved
PREMARIN VAGINAL CREAM
0.625MG · CREAM · PFIZER CANADA ULC
DIN 02043440 · ended Dec 7, 2021 · Disruption of the manufacture of the drug.
Resolved
PREMARIN VAGINAL CREAM
0.625MG · CREAM · PFIZER CANADA INC
DIN 02043440 · ended Dec 17, 2018 · Demand increase for the drug.
Discontinued
PREMARIN VAGINAL CREAM
0.625MG · CREAM · PFIZER CANADA INC
DIN 02043440
Resolved
PREMARIN VAGINAL CREAM
0.625MG · CREAM · PFIZER CANADA INC
DIN 02043440 · ended May 16, 2018 · New 30 gram tube presentation is fully available.
Resolved
PREMARIN VAGINAL CREAM
0.625MG · CREAM · PFIZER CANADA INC
DIN 02043440 · ended Nov 21, 2017 · Disruption of the manufacture of the drug.
Showing 12 of 13 reports. All reports are on file with Health Canada.
What's happening
Conjugated Estrogens is currently affected by an active shortage report filed with Health Canada by PFIZER CANADA ULC.
The reported cause is: disruption of the manufacture of the drug. Manufacturers must report shortages, but end-date estimates are their own projections and often move.
If your usual product is affected, a pharmacist is the fastest route to a solution: they can dispense an unaffected manufacturer's equivalent when one exists, and in most provinces can adapt doses or substitute a therapeutic alternative without a new appointment.
Conjugated Estrogens is classified under “ESTROGENS” (ATC G03CA).
Recent changes
Aug 18, 2026
Status changed
Common questions
What is Conjugated Estrogens used for?
An estrogen hormone therapy used to relieve menopausal symptoms.
When will Conjugated Estrogens be back in stock in Canada?
Manufacturers have not provided a reliable end date. This page updates automatically as soon as an estimate is filed.
Why is Conjugated Estrogens in shortage?
See the reports above; manufacturers must state a reason (most commonly manufacturing disruption or a surge in demand) when filing with Health Canada.
What can my pharmacist do about it?
Often quite a lot: substitute an equivalent product from an unaffected manufacturer, adjust quantities, or in most provinces adapt or renew prescriptions on the spot. Call your pharmacy before visiting, and call 811 for free health advice.
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Possible alternatives in the same class (estrogens)
Drugs in the same therapeutic class, best-supplied first. These are not automatic substitutes: only your pharmacist or prescriber can judge whether a switch makes sense for you.
Data reflects reports manufacturers are legally required to file with Health Canada, republished with per-drug aggregation by rxstat. Estimated end dates are supplied by manufacturers and frequently change. This page describes drug supply only and is not medical advice; never stop or switch a medication without speaking to your pharmacist or prescriber.