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Andexanet Alfa (Ondexxya) shortage status

Partial shortage

Source: Health Canada shortage reports · Updated Aug 11, 2026

Some Andexanet Alfa products are in shortage in Canada (1 of 1 reported products), while others remain available. Your pharmacy may be able to substitute an unaffected manufacturer. The latest estimate for affected products to return is Aug 30, 2026.
Products affected
1 / 1
In shortage since
Aug 7, 2026
Est. full return
Aug 30, 2026
Reports on file
1
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Reports by product

Active shortage
ONDEXXYA
200MG · POWDER FOR SOLUTION · ASTRAZENECA CANADA INC
DIN 02538539 · since Aug 7, 2026, est. end Aug 30, 2026 · Delay in shipping of the drug.

What's happening

Andexanet Alfa is currently affected by an active shortage report filed with Health Canada by ASTRAZENECA CANADA INC.

The reported cause is: delay in shipping of the drug. Manufacturers must report shortages, but end-date estimates are their own projections and often move.

If your usual product is affected, a pharmacist is the fastest route to a solution: they can dispense an unaffected manufacturer's equivalent when one exists, and in most provinces can adapt doses or substitute a therapeutic alternative without a new appointment.

Recent changes

Common questions

When will Andexanet Alfa be back in stock in Canada?

The latest manufacturer estimate is Aug 30, 2026. Estimates are self-reported and often slip; this page updates automatically when they change.

Why is Andexanet Alfa in shortage?

See the reports above; manufacturers must state a reason (most commonly manufacturing disruption or a surge in demand) when filing with Health Canada.

What can my pharmacist do about it?

Often quite a lot: substitute an equivalent product from an unaffected manufacturer, adjust quantities, or in most provinces adapt or renew prescriptions on the spot. Call your pharmacy before visiting, and call 811 for free health advice.

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Possible alternatives in the same class

Drugs in the same therapeutic class, best-supplied first. These are not automatic substitutes: only your pharmacist or prescriber can judge whether a switch makes sense for you.

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Guides: what to do when your medication is in shortage · how to read shortage reports

Data reflects reports manufacturers are legally required to file with Health Canada, republished with per-drug aggregation by rxstat. Estimated end dates are supplied by manufacturers and frequently change. This page describes drug supply only and is not medical advice; never stop or switch a medication without speaking to your pharmacist or prescriber.