Dexrazoxane (Zinecard) shortage status

Partial shortage

Source: Health Canada shortage reports · Updated Jul 9, 2026

Some Dexrazoxane products are in shortage in Canada (1 of 3 reported products), while others remain available. Your pharmacy may be able to substitute an unaffected manufacturer.

A medication used to protect the heart from damage caused by certain chemotherapy drugs.

Products affected

1 / 3

In shortage since

Dec 15, 2016

Reports on file

Talk to a pharmacist

Pharmacists can substitute an unaffected manufacturer's version, adjust strengths, and in most provinces adapt or renew a prescription on the spot.

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Shortage history

Shortage history (red bands = periods in shortage).

Reports by product

The DIN is printed on your prescription label.

Active shortage

ZINECARD

500MG · POWDER FOR SOLUTION · PFIZER CANADA INC

DIN 02153440 · since Dec 15, 2016, no end estimate · Disruption of the manufacture of the drug.

Resolved

DEXRAZOXANE FOR INJECTION

250MG · POWDER FOR SOLUTION · JUNO PHARMACEUTICALS CORP.

DIN 02544083 · ended Mar 2, 2026 · Disruption of the manufacture of the drug.

Resolved

ZINECARD

250MG · POWDER FOR SOLUTION · PFIZER CANADA ULC

DIN 02153432 · ended Oct 4, 2023 · Disruption of the manufacture of the drug.

Resolved

ZINECARD

250MG · POWDER FOR SOLUTION · PFIZER CANADA ULC

DIN 02153432 · ended Feb 16, 2021 · Disruption of the manufacture of the drug.

Resolved

ZINECARD

250MG · POWDER FOR SOLUTION · PFIZER CANADA ULC

DIN 02153432 · ended Sep 9, 2019 · Disruption of the manufacture of the drug.

Resolved

ZINECARD

250MG · POWDER FOR SOLUTION · PFIZER CANADA INC

DIN 02153432 · ended Jun 5, 2018 · Disruption of the manufacture of the drug.

What's happening

Dexrazoxane is currently affected by an active shortage report filed with Health Canada by PFIZER CANADA INC.

The reported cause is: disruption of the manufacture of the drug. Manufacturers must report shortages, but end-date estimates are their own projections and often move.

If your usual product is affected, a pharmacist is the fastest route to a solution: they can dispense an unaffected manufacturer's equivalent when one exists, and in most provinces can adapt doses or substitute a therapeutic alternative without a new appointment.

Dexrazoxane is classified under “ALL OTHER THERAPEUTIC PRODUCTS” (ATC V03AF).

Recent changes

No changes recorded yet.

Common questions

What is Dexrazoxane used for?

A medication used to protect the heart from damage caused by certain chemotherapy drugs.

When will Dexrazoxane be back in stock in Canada?

Manufacturers have not provided a reliable end date. This page updates automatically as soon as an estimate is filed.

Why is Dexrazoxane in shortage?

See the reports above; manufacturers must state a reason (most commonly manufacturing disruption or a surge in demand) when filing with Health Canada.

What can my pharmacist do about it?

Often quite a lot: substitute an equivalent product from an unaffected manufacturer, adjust quantities, or in most provinces adapt or renew prescriptions on the spot. Call your pharmacy before visiting, and call 811 for free health advice.

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Possible alternatives in the same class (all other therapeutic products)

Drugs in the same therapeutic class, best-supplied first. These are not automatic substitutes: only your pharmacist or prescriber can judge whether a switch makes sense for you.

Deferoxamine (Desferal) No current shortage Digoxin Immune Fab (Digifab) No current shortage Protamine No current shortage Sevelamer (Renagel) No current shortage Sevelamer Carbonate (Renvela) No current shortage Deferasirox Partial shortage 1 of 21 reported products affected

Guides: what to do when your medication is in shortage · how to read shortage reports

Data reflects reports manufacturers are legally required to file with Health Canada, republished with per-drug aggregation by rxstat. Estimated end dates are supplied by manufacturers and frequently change. This page describes drug supply only and is not medical advice; never stop or switch a medication without speaking to your pharmacist or prescriber.