rxstatShortages › Zoledronic Acid

Zoledronic Acid (Zometa, Aclasta) shortage status

Partial shortage

Source: Health Canada shortage reports · Updated Jul 9, 2026

Some Zoledronic Acid products are in shortage in Canada (2 of 14 reported products), while others remain available. Your pharmacy may be able to substitute an unaffected manufacturer.

A bisphosphonate used to treat osteoporosis and bone problems.

Products affected
2 / 14
In shortage since
May 27, 2025
Reports on file
36
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Pharmacists can substitute an unaffected manufacturer's version, adjust strengths, and in most provinces adapt or renew a prescription on the spot.
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Shortage history

2023 2024 2025 2026

Shortage history (red bands = periods in shortage).

Reports by product

The DIN is printed on your prescription label.

Active shortage
ZOLEDRONIC ACID FOR INJECTION
4MG · SOLUTION · FRESENIUS KABI CANADA LTD
DIN 02434458 · since ?, est. end Jul 6, 2026 · Disruption of the manufacture of the drug.
Active shortage
ZOMETA CONCENTRATE
4MG · SOLUTION · NOVARTIS PHARMACEUTICALS CANADA INC
DIN 02248296 · since May 27, 2025, no end estimate · Disruption of the manufacture of the drug.
To be discontinued
ZOLEDRONIC ACID - Z
4MG · SOLUTION · SANDOZ CANADA INCORPORATED
DIN 02401606
Resolved
ZOLEDRONIC ACID - Z
4MG · SOLUTION · SANDOZ CANADA INCORPORATED
DIN 02401606 · ended Jun 23, 2025 · Demand increase for the drug.
Discontinued
ZOLEDRONIC ACID FOR INJECTION
4MG · SOLUTION · TEVA CANADA LIMITED
DIN 02407639
Resolved
ACLASTA
5MG · SOLUTION · SANDOZ CANADA INCORPORATED
DIN 02269198 · ended May 19, 2025 · Requirements related to complying with good manufacturing practices.
Resolved
ZOLEDRONIC ACID - Z
4MG · SOLUTION · SANDOZ CANADA INCORPORATED
DIN 02401606 · ended Mar 31, 2025 · Demand increase for the drug.
Resolved
TARO-ZOLEDRONIC ACID
5MG · SOLUTION · TARO PHARMACEUTICALS INC
DIN 02415100 · ended Jul 1, 2024 · Recall with no back up inventory currently available
Discontinued
TARO-ZOLEDRONIC ACID
5MG · SOLUTION · TARO PHARMACEUTICALS INC
DIN 02415100
Resolved
TARO-ZOLEDRONIC ACID CONCENTRATE
4MG · SOLUTION · TARO PHARMACEUTICALS INC
DIN 02415186 · ended Nov 28, 2023 · Disruption of the manufacture of the drug.
Resolved
JAMP-ZOLEDRONIC ACID
4MG · SOLUTION · JAMP PHARMA CORPORATION
DIN 02482525 · ended Oct 10, 2023 · Disruption of the manufacture of the drug.
Resolved
ZOLEDRONIC ACID FOR INJECTION
4MG · SOLUTION · TEVA CANADA LIMITED
DIN 02407639 · ended Jun 30, 2020 · Disruption of the manufacture of the drug.

Showing 12 of 36 reports. All reports are on file with Health Canada.

What's happening

Zoledronic Acid is currently affected by 2 active shortage reports filed with Health Canada by FRESENIUS KABI CANADA LTD, NOVARTIS PHARMACEUTICALS CANADA INC.

The reported cause is: disruption of the manufacture of the drug. Manufacturers must report shortages, but end-date estimates are their own projections and often move.

If your usual product is affected, a pharmacist is the fastest route to a solution: they can dispense an unaffected manufacturer's equivalent when one exists, and in most provinces can adapt doses or substitute a therapeutic alternative without a new appointment.

Zoledronic Acid is classified under “DRUGS AFFECTING BONE STRUCTURE AND MINERALIZATION” (ATC M05BA).

Recent changes

Common questions

What is Zoledronic Acid used for?

A bisphosphonate used to treat osteoporosis and bone problems.

When will Zoledronic Acid be back in stock in Canada?

Manufacturers have not provided a reliable end date. This page updates automatically as soon as an estimate is filed.

Why is Zoledronic Acid in shortage?

See the reports above; manufacturers must state a reason (most commonly manufacturing disruption or a surge in demand) when filing with Health Canada.

What can my pharmacist do about it?

Often quite a lot: substitute an equivalent product from an unaffected manufacturer, adjust quantities, or in most provinces adapt or renew prescriptions on the spot. Call your pharmacy before visiting, and call 811 for free health advice.

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Possible alternatives in the same class (drugs affecting bone structure and mineralization)

Drugs in the same therapeutic class, best-supplied first. These are not automatic substitutes: only your pharmacist or prescriber can judge whether a switch makes sense for you.

Guides: what to do when your medication is in shortage · how to read shortage reports

Data reflects reports manufacturers are legally required to file with Health Canada, republished with per-drug aggregation by rxstat. Estimated end dates are supplied by manufacturers and frequently change. This page describes drug supply only and is not medical advice; never stop or switch a medication without speaking to your pharmacist or prescriber.