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Valproic Acid shortage status

Partial shortage

Source: Health Canada shortage reports · Updated Jul 9, 2026

Some Valproic Acid products are in shortage in Canada (3 of 24 reported products), while others remain available. Your pharmacy may be able to substitute an unaffected manufacturer. The latest estimate for affected products to return is Dec 30, 2026.
Products affected
3 / 24
In shortage since
Jan 26, 2022
Est. full return
Dec 30, 2026
Reports on file
86
Talk to your pharmacist. Pharmacists can often substitute another manufacturer's version, a different strength, or (in most provinces) adapt or renew a prescription on the spot. Your free provincial health line is 811.

Reports by product

Active shortage
PMS-VALPROIC ACID
250MG · CAPSULE · PHARMASCIENCE INC
DIN 02230768 · since Mar 16, 2025, est. end Dec 30, 2026 · Disruption of the manufacture of the drug.
Active shortage
PMS-VALPROIC ACID E.C.
500MG · CAPSULE (ENTERIC-COATED) · PHARMASCIENCE INC
DIN 02229628 · since Jan 26, 2022, no end estimate · Disruption of the manufacture of the drug.
Active shortage
APO-VALPROIC ACID ORAL SOLUTION
250MG · SOLUTION · APOTEX INC
DIN 02238370 · since Sep 5, 2023, no end estimate · Disruption of the manufacture of the drug.
Resolved
JAMP VALPROIC ACID ORAL SOLUTION
250MG · SOLUTION · JAMP PHARMA CORPORATION
DIN 02532441 · ended May 28, 2026 · Disruption of the manufacture of the drug.
Resolved
APO-DIVALPROEX
500MG · TABLET (DELAYED-RELEASE) TABLET (ENTERIC-COATED) · APOTEX INC
DIN 02239700 · ended Aug 15, 2024 · Disruption of the manufacture of the drug.
Resolved
DEPAKENE
250MG · SOLUTION SOLUTION · BGP PHARMA ULC
DIN 00443832 · ended Aug 6, 2024 · Disruption of the manufacture of the drug.
Discontinued
APO-VALPROIC ACID ORAL SOLUTION
250MG · SOLUTION · APOTEX INC
DIN 02238370
Resolved
APO-DIVALPROEX
250MG · TABLET (DELAYED-RELEASE) TABLET (ENTERIC-COATED) · APOTEX INC
DIN 02239699 · ended Oct 26, 2023 · Disruption of the manufacture of the drug.
Resolved
APO-DIVALPROEX
500MG · TABLET (DELAYED-RELEASE) TABLET (ENTERIC-COATED) · APOTEX INC
DIN 02239700 · ended Sep 21, 2023 · Disruption of the manufacture of the drug.
Resolved
APO-DIVALPROEX
125MG · TABLET (DELAYED-RELEASE) TABLET (ENTERIC-COATED) · APOTEX INC
DIN 02239698 · ended Aug 31, 2023 · Disruption of the manufacture of the drug.
Resolved
APO-DIVALPROEX
500MG · TABLET (DELAYED-RELEASE) TABLET (ENTERIC-COATED) · APOTEX INC
DIN 02239700 · ended Jul 4, 2023 · Disruption of the manufacture of the drug.
Resolved
APO-DIVALPROEX
250MG · TABLET (DELAYED-RELEASE) TABLET (ENTERIC-COATED) · APOTEX INC
DIN 02239699 · ended Jul 4, 2023 · Disruption of the manufacture of the drug.

Showing 12 of 60 reports. All reports are on file with Health Canada.

What's happening

Valproic Acid is currently affected by 3 active shortage reports filed with Health Canada by PHARMASCIENCE INC, APOTEX INC.

The reported cause is: disruption of the manufacture of the drug. Manufacturers must report shortages, but end-date estimates are their own projections and often move.

If your usual product is affected, a pharmacist is the fastest route to a solution: they can dispense an unaffected manufacturer's equivalent when one exists, and in most provinces can adapt doses or substitute a therapeutic alternative without a new appointment.

Valproic Acid is classified under “ANTIEPILEPTICS” (ATC N03AG).

Recent changes

Common questions

When will Valproic Acid be back in stock in Canada?

The latest manufacturer estimate is Dec 30, 2026. Estimates are self-reported and often slip; this page updates automatically when they change.

Why is Valproic Acid in shortage?

See the reports above; manufacturers must state a reason (most commonly manufacturing disruption or a surge in demand) when filing with Health Canada.

What can my pharmacist do about it?

Often quite a lot: substitute an equivalent product from an unaffected manufacturer, adjust quantities, or in most provinces adapt or renew prescriptions on the spot. Call your pharmacy before visiting, and call 811 for free health advice.

Related drugs (antiepileptics)

Partial shortageBrivaracetam1 of 8 reported products affected · est. return Apr 3, 2026Partial shortageCarbamazepine2 of 20 reported products affected · est. return Jun 26, 2026Partial shortageClonazepam5 of 21 reported products affectedPartial shortageLacosamide6 of 34 reported products affected · est. return Aug 10, 2026Partial shortageLevetiracetam13 of 48 reported products affected · est. return Sep 11, 2026Partial shortageOxcarbazepine3 of 8 reported products affected · est. return Dec 30, 2022

Guides: what to do when your medication is in shortage · how to read shortage reports

Data reflects reports manufacturers are legally required to file with Health Canada, republished with per-drug aggregation by rxstat. Estimated end dates are supplied by manufacturers and frequently change. This page describes drug supply only and is not medical advice; never stop or switch a medication without speaking to your pharmacist or prescriber.