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Tryptophan shortage status

Partial shortage

Source: Health Canada shortage reports · Updated Jul 9, 2026

Some Tryptophan products are in shortage in Canada (2 of 11 reported products), while others remain available. Your pharmacy may be able to substitute an unaffected manufacturer. The latest estimate for affected products to return is Jun 26, 2026.
Products affected
2 / 11
In shortage since
Aug 7, 2024
Est. full return
Jun 26, 2026
Reports on file
38
Talk to your pharmacist. Pharmacists can often substitute another manufacturer's version, a different strength, or (in most provinces) adapt or renew a prescription on the spot. Your free provincial health line is 811.

Reports by product

Active shortage
APO-TRYPTOPHAN
500MG · TABLET · APOTEX INC
DIN 02248538 · since Apr 28, 2026, est. end Jun 26, 2026 · Disruption of the manufacture of the drug.
Active shortage
TEVA-TRYPTOPHAN
500MG · CAPSULE · TEVA CANADA LIMITED
DIN 02240334 · since Aug 7, 2024, no end estimate · Disruption of the manufacture of the drug.
To be discontinued
TRYPTAN
750MG · TABLET · BAUSCH HEALTH, CANADA INC.
DIN 02239327
To be discontinued
TRYPTAN
1G · TABLET · BAUSCH HEALTH, CANADA INC.
DIN 00654531
Discontinued
TEVA-TRYPTOPHAN
500MG · TABLET · TEVA CANADA LIMITED
DIN 02240333
Discontinued
TEVA-TRYPTOPHAN
500MG · TABLET · TEVA CANADA LIMITED
DIN 02240333
Discontinued
TEVA-TRYPTOPHAN
1G · TABLET · TEVA CANADA LIMITED
DIN 02237250
Discontinued
TEVA-TRYPTOPHAN
500MG · TABLET · TEVA CANADA LIMITED
DIN 02240333
Resolved
TRYPTAN
500MG · TABLET · BAUSCH HEALTH, CANADA INC.
DIN 02029456 · ended May 30, 2024 · Other (Please describe in comments)
Resolved
TRYPTAN
250MG · TABLET · BAUSCH HEALTH, CANADA INC.
DIN 02239326 · ended May 30, 2024 · Other (Please describe in comments)
Resolved
APO-TRYPTOPHAN
500MG · TABLET · APOTEX INC
DIN 02248538 · ended Apr 4, 2024 · Disruption of the manufacture of the drug.
Resolved
APO-TRYPTOPHAN
1G · TABLET · APOTEX INC
DIN 02248539 · ended Apr 4, 2024 · Disruption of the manufacture of the drug.

Showing 12 of 38 reports. All reports are on file with Health Canada.

What's happening

Tryptophan is currently affected by 2 active shortage reports filed with Health Canada by APOTEX INC, TEVA CANADA LIMITED.

The reported cause is: disruption of the manufacture of the drug. Manufacturers must report shortages, but end-date estimates are their own projections and often move.

If your usual product is affected, a pharmacist is the fastest route to a solution: they can dispense an unaffected manufacturer's equivalent when one exists, and in most provinces can adapt doses or substitute a therapeutic alternative without a new appointment.

Tryptophan is classified under “ANTIDEPRESSANTS” (ATC N06AX).

Recent changes

Common questions

When will Tryptophan be back in stock in Canada?

The latest manufacturer estimate is Jun 26, 2026. Estimates are self-reported and often slip; this page updates automatically when they change.

Why is Tryptophan in shortage?

See the reports above; manufacturers must state a reason (most commonly manufacturing disruption or a surge in demand) when filing with Health Canada.

What can my pharmacist do about it?

Often quite a lot: substitute an equivalent product from an unaffected manufacturer, adjust quantities, or in most provinces adapt or renew prescriptions on the spot. Call your pharmacy before visiting, and call 811 for free health advice.

Related drugs (antidepressants)

Widespread shortageClomipramine3 of 4 reported products affected · est. return Jul 3, 2026Widespread shortageImipramine3 of 6 reported products affected · est. return Aug 28, 2026Partial shortageAmitriptyline15 of 34 reported products affected · est. return Jul 17, 2026Partial shortageBupropion3 of 15 reported products affected · est. return Jul 15, 2026Partial shortageCitalopram10 of 43 reported products affected · est. return Sep 30, 2026Partial shortageDesvenlafaxine2 of 17 reported products affected · est. return Jul 31, 2026

Guides: what to do when your medication is in shortage · how to read shortage reports

Data reflects reports manufacturers are legally required to file with Health Canada, republished with per-drug aggregation by rxstat. Estimated end dates are supplied by manufacturers and frequently change. This page describes drug supply only and is not medical advice; never stop or switch a medication without speaking to your pharmacist or prescriber.