rxstat › Shortages › Tetracosactide

Tetracosactide (Synacthen Depot, Cortrosyn) shortage status

Partial shortage

Source: Health Canada shortage reports · Updated Jul 9, 2026

Some Tetracosactide products are in shortage in Canada (1 of 2 reported products), while others remain available. Your pharmacy may be able to substitute an unaffected manufacturer.

A synthetic ACTH used to test how well the adrenal glands are working.

Products affected
1 / 2
Reports on file
5
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Pharmacists can substitute an unaffected manufacturer's version, adjust strengths, and in most provinces adapt or renew a prescription on the spot.
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Reports by product

The DIN is printed on your prescription label.

Active shortage
SYNACTHEN DEPOT
1MG · SUSPENSION · MALLINCKRODT SPECIALTY PHARMACEUTICALS IRELAND LTD.
DIN 00253952 · since ?, no end estimate · Disruption of the manufacture of the drug.
Resolved
CORTROSYN INJ 0.25MG
0.25MG · POWDER FOR SOLUTION · AMPHASTAR PHARMACEUTICALS, INC.
DIN 00022381 · ended Jun 27, 2022 · Demand increase for the drug.
Resolved
CORTROSYN INJ 0.25MG
0.25MG · POWDER FOR SOLUTION · AMPHASTAR PHARMACEUTICALS, INC.
DIN 00022381 · ended Apr 29, 2022 · manufacturing delay
Resolved
CORTROSYN INJ 0.25MG
0.25MG · POWDER FOR SOLUTION · AMPHASTAR PHARMACEUTICALS, INC.
DIN 00022381 · ended Jan 18, 2022 · Disruption of the manufacture of the drug.
Resolved
CORTROSYN INJ 0.25MG
0.25MG · POWDER FOR SOLUTION · AMPHASTAR PHARMACEUTICALS, INC.
DIN 00022381 · ended Apr 3, 2018 · Unexpected delay in manufacturing.

What's happening

Tetracosactide is currently affected by an active shortage report filed with Health Canada by MALLINCKRODT SPECIALTY PHARMACEUTICALS IRELAND LTD..

The reported cause is: disruption of the manufacture of the drug. Manufacturers must report shortages, but end-date estimates are their own projections and often move.

If your usual product is affected, a pharmacist is the fastest route to a solution: they can dispense an unaffected manufacturer's equivalent when one exists, and in most provinces can adapt doses or substitute a therapeutic alternative without a new appointment.

Tetracosactide is classified under “ANTERIOR PITUITARY LOBE HORMONES AND ANALOGUES” (ATC H01AA).

Recent changes

Common questions

What is Tetracosactide used for?

A synthetic ACTH used to test how well the adrenal glands are working.

When will Tetracosactide be back in stock in Canada?

Manufacturers have not provided a reliable end date. This page updates automatically as soon as an estimate is filed.

Why is Tetracosactide in shortage?

See the reports above; manufacturers must state a reason (most commonly manufacturing disruption or a surge in demand) when filing with Health Canada.

What can my pharmacist do about it?

Often quite a lot: substitute an equivalent product from an unaffected manufacturer, adjust quantities, or in most provinces adapt or renew prescriptions on the spot. Call your pharmacy before visiting, and call 811 for free health advice.

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Possible alternatives in the same class (anterior pituitary lobe hormones and analogues)

Drugs in the same therapeutic class, best-supplied first. These are not automatic substitutes: only your pharmacist or prescriber can judge whether a switch makes sense for you.

Somatropin (Genotropin) Shortage anticipated 0 of 27 reported products affected Chloride Somatropin (Saizen) Discontinued 0 of 1 reported products affected Somatropin Diluent (Humatrope) Discontinued 0 of 3 reported products affected Tesamorelin (Egrifta) Discontinued 0 of 1 reported products affected

Guides: what to do when your medication is in shortage · how to read shortage reports

Data reflects reports manufacturers are legally required to file with Health Canada, republished with per-drug aggregation by rxstat. Estimated end dates are supplied by manufacturers and frequently change. This page describes drug supply only and is not medical advice; never stop or switch a medication without speaking to your pharmacist or prescriber.