rxstat › Shortages › Tacrolimus
Tacrolimus shortage status
Partial shortage
Source: Health Canada shortage reports · Updated Jul 9, 2026
Some Tacrolimus products are in shortage in Canada (2 of 6 reported products), while others remain available. Your pharmacy may be able to substitute an unaffected manufacturer.
In shortage since
Dec 1, 2023
Talk to your pharmacist. Pharmacists can often substitute another manufacturer's version, a different strength, or (in most provinces) adapt or renew a prescription on the spot. Your free provincial health line is 811.
Reports by product
Active shortageACH-TACROLIMUS
1MG · CAPSULE (IMMEDIATE RELEASE) · ACCORD HEALTHCARE INC
DIN 02456095 · since Jan 8, 2025, no end estimate · Requirements related to complying with good manufacturing practices.
Active shortageACH-TACROLIMUS
0.5MG · CAPSULE (IMMEDIATE RELEASE) · ACCORD HEALTHCARE INC
DIN 02454068 · since Dec 1, 2023, no end estimate · Disruption of the manufacture of the drug.
ResolvedSANDOZ TACROLIMUS
1MG · CAPSULE (IMMEDIATE RELEASE) · SANDOZ CANADA INCORPORATED
DIN 02416824 · ended Nov 28, 2025 · Delay in shipping of the drug.
DiscontinuedPROTOPIC
0.03% · OINTMENT · LEO PHARMA INC
DIN 02244149
DiscontinuedPROTOPIC
0.1% · OINTMENT · LEO PHARMA INC
DIN 02244148
ResolvedPROTOPIC
0.03% · OINTMENT · LEO PHARMA INC
DIN 02244149 · ended Apr 15, 2025 · Other (Please describe in comments)
ResolvedPROTOPIC
0.1% · OINTMENT · LEO PHARMA INC
DIN 02244148 · ended Apr 15, 2025 · Other (Please describe in comments)
ResolvedSANDOZ TACROLIMUS
0.5MG · CAPSULE (IMMEDIATE RELEASE) · SANDOZ CANADA INCORPORATED
DIN 02416816 · ended Oct 30, 2023 · Disruption of the manufacture of the drug.
ResolvedPROTOPIC
0.1% · OINTMENT · LEO PHARMA INC
DIN 02244148 · ended Sep 17, 2019 · Disruption of the manufacture of the drug.
ResolvedPROTOPIC
0.03% · OINTMENT · LEO PHARMA INC
DIN 02244149 · ended Aug 2, 2019 · Disruption of the manufacture of the drug.
ResolvedPROTOPIC
0.1% · OINTMENT · LEO PHARMA INC
DIN 02244148 · ended Apr 17, 2019 · Disruption of the manufacture of the drug.
ResolvedPROTOPIC
0.1% · OINTMENT · LEO PHARMA INC
DIN 02244148 · ended Dec 20, 2018 · Delay in shipping of the drug.
Showing 12 of 13 reports. All reports are on file with Health Canada.
What's happening
Tacrolimus is currently affected by 2 active shortage reports filed with Health Canada by ACCORD HEALTHCARE INC.
The reported causes are: requirements related to complying with good manufacturing practices; disruption of the manufacture of the drug. Manufacturers must report shortages, but end-date estimates are their own projections and often move.
If your usual product is affected, a pharmacist is the fastest route to a solution: they can dispense an unaffected manufacturer's equivalent when one exists, and in most provinces can adapt doses or substitute a therapeutic alternative without a new appointment.
Tacrolimus is classified under “IMMUNOSUPPRESSANTS” (ATC L04AD).
Recent changes
Common questions
When will Tacrolimus be back in stock in Canada?
Manufacturers have not provided a reliable end date. This page updates automatically as soon as an estimate is filed.
Why is Tacrolimus in shortage?
See the reports above; manufacturers must state a reason (most commonly manufacturing disruption or a surge in demand) when filing with Health Canada.
What can my pharmacist do about it?
Often quite a lot: substitute an equivalent product from an unaffected manufacturer, adjust quantities, or in most provinces adapt or renew prescriptions on the spot. Call your pharmacy before visiting, and call 811 for free health advice.
Guides: what to do when your medication is in shortage · how to read shortage reports
Data reflects reports manufacturers are legally required to file with Health Canada, republished with per-drug aggregation by rxstat. Estimated end dates are supplied by manufacturers and frequently change. This page describes drug supply only and is not medical advice; never stop or switch a medication without speaking to your pharmacist or prescriber.