Source: Health Canada shortage reports · Updated Jul 9, 2026
Protamine has no current shortage reported in Canada. It has been in shortage before; the history is below.
A medicine used to reverse the blood-thinning effect of heparin.
Products affected
0 / 2
Reports on file
16
Shortage history
Shortage history (red bands = periods in shortage).
Reports by product
The DIN is printed on your prescription label.
Resolved
PROTAMINE SULFATE INJECTION USP
10MG · SOLUTION · SANDOZ CANADA INCORPORATED
DIN 02231674 · ended Jan 8, 2026 · Delay in shipping of the drug.
Resolved
PROTAMINE SULFATE INJECTION USP
10MG · SOLUTION · SANDOZ CANADA INCORPORATED
DIN 02231674 · ended Oct 3, 2025 · Demand increase for the drug.
Resolved
PROTAMINE SULFATE INJECTION USP
10MG · SOLUTION · SANDOZ CANADA INCORPORATED
DIN 02231674 · ended Jul 7, 2025 · Demand increase for the drug.
Resolved
PROTAMINE SULFATE INJECTION USP
10MG · SOLUTION · SANDOZ CANADA INCORPORATED
DIN 02231674 · ended Jan 16, 2024 · Disruption of the manufacture of the drug.
Resolved
PROTAMINE SULFATE INJECTION USP
10MG · SOLUTION · SANDOZ CANADA INCORPORATED
DIN 02231674 · ended Aug 29, 2023 · Disruption of the manufacture of the drug.
Resolved
PROTAMINE SULFATE INJECTION, USP
10MG · SOLUTION · FRESENIUS KABI CANADA LTD
DIN 02139537 · ended Aug 15, 2023
Resolved
PROTAMINE SULFATE INJECTION, USP
10MG · SOLUTION · FRESENIUS KABI CANADA LTD
DIN 02139537 · ended Sep 30, 2022 · Disruption of the manufacture of the drug.
Resolved
PROTAMINE SULFATE INJECTION, USP
10MG · SOLUTION · FRESENIUS KABI CANADA LTD
DIN 02139537 · ended Sep 7, 2022 · Disruption of the manufacture of the drug.
Resolved
PROTAMINE SULFATE INJECTION USP
10MG · SOLUTION · SANDOZ CANADA INCORPORATED
DIN 02231674 · ended Aug 18, 2022 · Disruption of the manufacture of the drug.
Resolved
PROTAMINE SULFATE INJECTION, USP
10MG · SOLUTION · FRESENIUS KABI CANADA LTD
DIN 02139537 · ended Mar 1, 2022 · Disruption of the manufacture of the drug.
Resolved
PROTAMINE SULFATE INJECTION, USP
10MG · SOLUTION · FRESENIUS KABI CANADA LTD
DIN 02139537 · ended Dec 24, 2021 · Delay in shipping of the drug.
Resolved
PROTAMINE SULFATE INJECTION, USP
10MG · SOLUTION · FRESENIUS KABI CANADA LTD
DIN 02139537 · ended Nov 30, 2021 · Disruption of the manufacture of the drug.
Showing 12 of 16 reports. All reports are on file with Health Canada.
What's happening
There are no active shortage reports for Protamine. Health Canada has 16 historical reports on file for this drug, so supply has been disrupted before; the change log below shows the history.
Protamine is classified under “ALL OTHER THERAPEUTIC PRODUCTS” (ATC V03AB).
Recent changes
No changes recorded yet.
Common questions
What is Protamine used for?
A medicine used to reverse the blood-thinning effect of heparin.
When will Protamine be back in stock in Canada?
Protamine has no active shortage; supply is normal per Health Canada reports.
Why is Protamine in shortage?
It isn't currently. Past reports and their reasons are listed above.
What can my pharmacist do about it?
Often quite a lot: substitute an equivalent product from an unaffected manufacturer, adjust quantities, or in most provinces adapt or renew prescriptions on the spot. Call your pharmacy before visiting, and call 811 for free health advice.
Email alerts
Get an email when this drug's status changes. Double opt-in, one-click unsubscribe.
Data reflects reports manufacturers are legally required to file with Health Canada, republished with per-drug aggregation by rxstat. Estimated end dates are supplied by manufacturers and frequently change. This page describes drug supply only and is not medical advice; never stop or switch a medication without speaking to your pharmacist or prescriber.