rxstatShortages › Pirfenidone

Pirfenidone (Esbriet) shortage status

Partial shortage

Source: Health Canada shortage reports · Updated Jul 9, 2026

Some Pirfenidone products are in shortage in Canada (3 of 10 reported products), while others remain available. Your pharmacy may be able to substitute an unaffected manufacturer. The latest estimate for affected products to return is Sep 19, 2026.

A medicine used to treat idiopathic pulmonary fibrosis, a scarring lung disease.

Products affected
3 / 10
In shortage since
May 23, 2024
Est. full return
Sep 19, 2026
Reports on file
23
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Shortage history

2023 2024 2025 2026

Shortage history (red bands = periods in shortage).

Reports by product

The DIN is printed on your prescription label.

Active shortage
SANDOZ PIRFENIDONE TABLETS
801MG · TABLET · SANDOZ CANADA INCORPORATED
DIN 02488515 · since Jul 6, 2026, est. end Sep 19, 2026 · Disruption of the manufacture of the drug.
Active shortage
PMS-PIRFENIDONE
801MG · TABLET · PHARMASCIENCE INC
DIN 02531534 · since May 23, 2024, no end estimate · Disruption of the manufacture of the drug.
Active shortage
PMS-PIRFENIDONE
267MG · TABLET · PHARMASCIENCE INC
DIN 02531526 · since May 23, 2024, no end estimate · Disruption of the manufacture of the drug.
Active shortage
PMS-PIRFENIDONE
267MG · TABLET · PHARMASCIENCE INC
DIN 02531526 · since May 23, 2024, no end estimate · Disruption of the manufacture of the drug.
Resolved
SANDOZ PIRFENIDONE CAPSULES
267MG · CAPSULE · SANDOZ CANADA INCORPORATED
DIN 02488833 · ended Mar 23, 2026 · Disruption of the manufacture of the drug.
Resolved
SANDOZ PIRFENIDONE TABLETS
267MG · TABLET · SANDOZ CANADA INCORPORATED
DIN 02488507 · ended Jan 30, 2026 · Disruption of the manufacture of the drug.
Resolved
SANDOZ PIRFENIDONE CAPSULES
267MG · CAPSULE · SANDOZ CANADA INCORPORATED
DIN 02488833 · ended Oct 28, 2024 · Disruption of the manufacture of the drug.
Resolved
SANDOZ PIRFENIDONE CAPSULES
267MG · CAPSULE · SANDOZ CANADA INCORPORATED
DIN 02488833 · ended Sep 30, 2024 · Disruption of the manufacture of the drug.
Resolved
SANDOZ PIRFENIDONE TABLETS
801MG · TABLET · SANDOZ CANADA INCORPORATED
DIN 02488515 · ended Jun 25, 2024 · Disruption of the manufacture of the drug.
Resolved
JAMP PIRFENIDONE
267MG · CAPSULE · JAMP PHARMA CORPORATION
DIN 02509938 · ended Apr 26, 2024 · Disruption of the manufacture of the drug.
Discontinued
ESBRIET
267MG · CAPSULE · HOFFMANN-LA ROCHE LIMITED
DIN 02393751
Discontinued
ESBRIET
267MG · CAPSULE · HOFFMANN-LA ROCHE LIMITED
DIN 02393751

Showing 12 of 23 reports. All reports are on file with Health Canada.

What's happening

Pirfenidone is currently affected by 3 active shortage reports filed with Health Canada by SANDOZ CANADA INCORPORATED, PHARMASCIENCE INC.

The reported cause is: disruption of the manufacture of the drug. Manufacturers must report shortages, but end-date estimates are their own projections and often move.

If your usual product is affected, a pharmacist is the fastest route to a solution: they can dispense an unaffected manufacturer's equivalent when one exists, and in most provinces can adapt doses or substitute a therapeutic alternative without a new appointment.

Pirfenidone is classified under “IMMUNOSUPPRESSANTS” (ATC L04AX).

Recent changes

Common questions

What is Pirfenidone used for?

A medicine used to treat idiopathic pulmonary fibrosis, a scarring lung disease.

When will Pirfenidone be back in stock in Canada?

The latest manufacturer estimate is Sep 19, 2026. Estimates are self-reported and often slip; this page updates automatically when they change.

Why is Pirfenidone in shortage?

See the reports above; manufacturers must state a reason (most commonly manufacturing disruption or a surge in demand) when filing with Health Canada.

What can my pharmacist do about it?

Often quite a lot: substitute an equivalent product from an unaffected manufacturer, adjust quantities, or in most provinces adapt or renew prescriptions on the spot. Call your pharmacy before visiting, and call 811 for free health advice.

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Possible alternatives in the same class (immunosuppressants)

Drugs in the same therapeutic class, best-supplied first. These are not automatic substitutes: only your pharmacist or prescriber can judge whether a switch makes sense for you.

Guides: what to do when your medication is in shortage · how to read shortage reports

Data reflects reports manufacturers are legally required to file with Health Canada, republished with per-drug aggregation by rxstat. Estimated end dates are supplied by manufacturers and frequently change. This page describes drug supply only and is not medical advice; never stop or switch a medication without speaking to your pharmacist or prescriber.