rxstatShortages › Peginterferon Alfa-2a

Peginterferon Alfa-2a (Pegasys) shortage status

Widespread shortage Tier 3: critical

Source: Health Canada shortage reports · Updated Jul 9, 2026

Peginterferon Alfa-2a is in a widespread shortage in Canada. 1 of 1 reported products are affected, and Health Canada has designated this a Tier 3 (most serious) shortage. Manufacturers have not committed to a recovery date.

An immune-modulating medication used to treat chronic hepatitis B and C.

Products affected
1 / 1
In shortage since
Oct 29, 2024
Reports on file
2
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Pharmacists can substitute an unaffected manufacturer's version, adjust strengths, and in most provinces adapt or renew a prescription on the spot.
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Shortage history

2025 2026

Shortage history (red bands = periods in shortage).

Reports by product

The DIN is printed on your prescription label.

Active shortage
PEGASYS
180MCG · SOLUTION · PHARMAAND GMBH
DIN 02248077 · since Oct 29, 2024, est. end Jun 30, 2026 · Disruption of the manufacture of the drug.
Discontinued
PEGASYS
180MCG · SOLUTION · HOFFMANN-LA ROCHE LIMITED
DIN 02248077

What's happening

Peginterferon Alfa-2a is currently affected by an active shortage report filed with Health Canada by PHARMAAND GMBH.

The reported cause is: disruption of the manufacture of the drug. Manufacturers must report shortages, but end-date estimates are their own projections and often move.

Health Canada has flagged this as a Tier 3 shortage, its most serious category, meaning the shortage has the greatest potential impact on the health system and alternatives are limited.

If your usual product is affected, a pharmacist is the fastest route to a solution: they can dispense an unaffected manufacturer's equivalent when one exists, and in most provinces can adapt doses or substitute a therapeutic alternative without a new appointment.

Peginterferon Alfa-2a is classified under “IMMUNOSTIMULANTS” (ATC L03AB).

Recent changes

Common questions

What is Peginterferon Alfa-2a used for?

An immune-modulating medication used to treat chronic hepatitis B and C.

When will Peginterferon Alfa-2a be back in stock in Canada?

Manufacturers have not provided a reliable end date. This page updates automatically as soon as an estimate is filed.

Why is Peginterferon Alfa-2a in shortage?

See the reports above; manufacturers must state a reason (most commonly manufacturing disruption or a surge in demand) when filing with Health Canada.

What can my pharmacist do about it?

Often quite a lot: substitute an equivalent product from an unaffected manufacturer, adjust quantities, or in most provinces adapt or renew prescriptions on the spot. Call your pharmacy before visiting, and call 811 for free health advice.

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Possible alternatives in the same class (immunostimulants)

Drugs in the same therapeutic class, best-supplied first. These are not automatic substitutes: only your pharmacist or prescriber can judge whether a switch makes sense for you.

Guides: what to do when your medication is in shortage · how to read shortage reports

Data reflects reports manufacturers are legally required to file with Health Canada, republished with per-drug aggregation by rxstat. Estimated end dates are supplied by manufacturers and frequently change. This page describes drug supply only and is not medical advice; never stop or switch a medication without speaking to your pharmacist or prescriber.