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Metolazone (Zaroxolyn) shortage status

Partial shortage

Source: Health Canada shortage reports · Updated Oct 27, 2026

Some Metolazone products are in shortage in Canada (1 of 1 reported products), while others remain available. Your pharmacy may be able to substitute an unaffected manufacturer. The latest estimate for affected products to return is Dec 18, 2026.

A diuretic (water pill) used to treat fluid retention and high blood pressure.

Products affected
1 / 1
In shortage since
Oct 26, 2026
Est. full return
Dec 18, 2026
Reports on file
4
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Pharmacists can substitute an unaffected manufacturer's version, adjust strengths, and in most provinces adapt or renew a prescription on the spot.
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Shortage history

2024 2025 2026

Shortage history (red bands = periods in shortage).

Reports by product

The DIN is printed on your prescription label.

Active shortage
ZAROXOLYN
2.5MG · TABLET · SANOFI-AVENTIS CANADA INC
DIN 00888400 · since Oct 26, 2026, est. end Dec 18, 2026
To be discontinued
ZAROXOLYN
2.5MG · TABLET · SANOFI-AVENTIS CANADA INC
DIN 00888400
reversed
ZAROXOLYN
2.5MG · TABLET · SANOFI-AVENTIS CANADA INC
DIN 00888400
Resolved
ZAROXOLYN
2.5MG · TABLET · SANOFI-AVENTIS CANADA INC
DIN 00888400 · ended May 9, 2023

What's happening

Metolazone is currently affected by an active shortage report filed with Health Canada by SANOFI-AVENTIS CANADA INC.

If your usual product is affected, a pharmacist is the fastest route to a solution: they can dispense an unaffected manufacturer's equivalent when one exists, and in most provinces can adapt doses or substitute a therapeutic alternative without a new appointment.

Metolazone is classified under “LOW-CEILING DIURETICS, EXCL THIAZIDES” (ATC C03BA).

Recent changes

Common questions

What is Metolazone used for?

A diuretic (water pill) used to treat fluid retention and high blood pressure.

When will Metolazone be back in stock in Canada?

The latest manufacturer estimate is Dec 18, 2026. Estimates are self-reported and often slip; this page updates automatically when they change.

Why is Metolazone in shortage?

See the reports above; manufacturers must state a reason (most commonly manufacturing disruption or a surge in demand) when filing with Health Canada.

What can my pharmacist do about it?

Often quite a lot: substitute an equivalent product from an unaffected manufacturer, adjust quantities, or in most provinces adapt or renew prescriptions on the spot. Call your pharmacy before visiting, and call 811 for free health advice.

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Possible alternatives in the same class (low-ceiling diuretics, excl thiazides)

Drugs in the same therapeutic class, best-supplied first. These are not automatic substitutes: only your pharmacist or prescriber can judge whether a switch makes sense for you.

Chlorthalidone Partial shortage 2 of 5 reported products affected · est. return Mar 31, 2027 Indapamide (Lozide) Partial shortage 2 of 14 reported products affected

Guides: what to do when your medication is in shortage · how to read shortage reports

Data reflects reports manufacturers are legally required to file with Health Canada, republished with per-drug aggregation by rxstat. Estimated end dates are supplied by manufacturers and frequently change. This page describes drug supply only and is not medical advice; never stop or switch a medication without speaking to your pharmacist or prescriber.