Leuprolide (Lupron Depot, Zeulide Depot) shortage status
Partial shortage
Source: Health Canada shortage reports · Updated Jul 9, 2026
Also sold as: Lupron Depot, Zeulide Depot, Lupron, Eligard
Some Leuprolide products are in shortage in Canada (1 of 8 reported products), while others remain available. Your pharmacy may be able to substitute an unaffected manufacturer.
A hormone therapy used to treat prostate cancer, endometriosis and uterine fibroids.
Products affected
1 / 8
Reports on file
13
Talk to a pharmacist
Pharmacists can substitute an unaffected manufacturer's version, adjust strengths, and in most provinces adapt or renew a prescription on the spot.
Independent services, not affiliated with rxstat; referral fees may apply. Free options exist depending on your province. In an emergency call 911; free health advice at 811.
Shortage history
Shortage history (red bands = periods in shortage).
Reports by product
The DIN is printed on your prescription label.
Active shortage
ZEULIDE DEPOT
3.75MG · KIT
POWDER FOR SUSPENSION, SUSTAINED-RELEASE · VERITY PHARMACEUTICALS INC.
DIN 02429977 · since ?, no end estimate · Delay in shipping of the drug.
Resolved
ZEULIDE DEPOT
22.5MG · KIT
POWDER FOR SUSPENSION, SUSTAINED-RELEASE · VERITY PHARMACEUTICALS INC.
DIN 02462699 · ended Aug 8, 2025 · Delay in shipping of the drug.
Resolved
ELIGARD
7.5MG · POWDER FOR SUSPENSION, SUSTAINED-RELEASE · TOLMAR INTERNATIONAL LTD.
DIN 02248239 · ended Sep 27, 2023 · Delay in shipping of the drug.
Discontinued
LUPRON
5MG · SOLUTION · ABBVIE CORPORATION
DIN 00727695
Resolved
ELIGARD
7.5MG · POWDER FOR SUSPENSION, EXTENDED-RELEASE · TOLMAR INTERNATIONAL LTD.
DIN 02248239 · ended May 20, 2022 · Delay in shipping of the drug.
Resolved
LUPRON DEPOT
11.25MG · POWDER FOR SUSPENSION, SUSTAINED-RELEASE · ABBVIE CORPORATION
DIN 02239834 · ended Mar 5, 2021 · Disruption of the manufacture of the drug.
Resolved
LUPRON DEPOT
30MG · POWDER FOR SUSPENSION, SUSTAINED-RELEASE · ABBVIE CORPORATION
DIN 02239833 · ended Mar 5, 2021 · Disruption of the manufacture of the drug.
Resolved
LUPRON DEPOT
3.75MG · POWDER FOR SUSPENSION, SUSTAINED-RELEASE · ABBVIE CORPORATION
DIN 00884502 · ended Jan 27, 2021 · Demand increase for the drug.
Resolved
LUPRON DEPOT
22.5MG · POWDER FOR SUSPENSION, SUSTAINED-RELEASE · ABBVIE CORPORATION
DIN 02230248 · ended Dec 11, 2020 · Disruption of the manufacture of the drug.
Resolved
LUPRON DEPOT
3.75MG · POWDER FOR SUSPENSION, SUSTAINED-RELEASE · ABBVIE CORPORATION
DIN 00884502 · ended Dec 6, 2019
Resolved
LUPRON DEPOT
22.5MG · POWDER FOR SUSPENSION, SUSTAINED-RELEASE · ABBVIE CORPORATION
DIN 02230248 · ended Dec 6, 2019
Resolved
LUPRON DEPOT
30MG · POWDER FOR SUSPENSION, SUSTAINED-RELEASE · ABBVIE CORPORATION
DIN 02239833 · ended Dec 6, 2019
Showing 12 of 13 reports. All reports are on file with Health Canada.
What's happening
Leuprolide is currently affected by an active shortage report filed with Health Canada by VERITY PHARMACEUTICALS INC..
The reported cause is: delay in shipping of the drug. Manufacturers must report shortages, but end-date estimates are their own projections and often move.
If your usual product is affected, a pharmacist is the fastest route to a solution: they can dispense an unaffected manufacturer's equivalent when one exists, and in most provinces can adapt doses or substitute a therapeutic alternative without a new appointment.
Leuprolide is classified under “HORMONES AND RELATED AGENTS” (ATC L02AE).
Recent changes
No changes recorded yet.
Common questions
What is Leuprolide used for?
A hormone therapy used to treat prostate cancer, endometriosis and uterine fibroids.
When will Leuprolide be back in stock in Canada?
Manufacturers have not provided a reliable end date. This page updates automatically as soon as an estimate is filed.
Why is Leuprolide in shortage?
See the reports above; manufacturers must state a reason (most commonly manufacturing disruption or a surge in demand) when filing with Health Canada.
What can my pharmacist do about it?
Often quite a lot: substitute an equivalent product from an unaffected manufacturer, adjust quantities, or in most provinces adapt or renew prescriptions on the spot. Call your pharmacy before visiting, and call 811 for free health advice.
Email alerts
Get an email when this drug's status changes. Double opt-in, one-click unsubscribe.
Drugs in the same therapeutic class, best-supplied first. These are not automatic substitutes: only your pharmacist or prescriber can judge whether a switch makes sense for you.
Data reflects reports manufacturers are legally required to file with Health Canada, republished with per-drug aggregation by rxstat. Estimated end dates are supplied by manufacturers and frequently change. This page describes drug supply only and is not medical advice; never stop or switch a medication without speaking to your pharmacist or prescriber.