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Letrozole shortage status

Partial shortage

Source: Health Canada shortage reports · Updated Jul 20, 2026

Some Letrozole products are in shortage in Canada (1 of 12 reported products), while others remain available. Your pharmacy may be able to substitute an unaffected manufacturer.

An aromatase inhibitor used to treat hormone receptor positive breast cancer.

Products affected
1 / 12
In shortage since
Aug 15, 2024
Reports on file
31
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Shortage history

2023 2024 2025 2026

Shortage history (red bands = periods in shortage).

Reports by product

The DIN is printed on your prescription label.

Active shortage
LETROZOLE
2.5MG · TABLET · SIVEM PHARMACEUTICALS ULC
DIN 02524244 · since Aug 15, 2024, no end estimate · Disruption of the manufacture of the drug.
Anticipated
SANDOZ LETROZOLE
2.5MG · TABLET · SANDOZ CANADA INCORPORATED
DIN 02344815 · Delay in shipping of the drug.
Resolved
MINT-LETROZOLE
2.5MG · TABLET · MINT PHARMACEUTICALS INC
DIN 02508109 · ended May 5, 2026 · Disruption of the manufacture of the drug.
Resolved
LETROZOLE
2.5MG · TABLET · SANIS HEALTH INC
DIN 02504472 · ended May 1, 2026 · Disruption of the manufacture of the drug.
Resolved
JAMP LETROZOLE TABLETS
2.5MG · TABLET · JAMP PHARMA CORPORATION
DIN 02541912 · ended Apr 1, 2026 · Disruption of the manufacture of the drug.
Resolved
ACH-LETROZOLE
2.5MG · TABLET · ACCORD HEALTHCARE INC
DIN 02338459 · ended Dec 29, 2025 · Requirements related to complying with good manufacturing practices.
Resolved
RIVA-LETROZOLE
2.5MG · TABLET · LABORATOIRE RIVA INC.
DIN 02398656 · ended Mar 27, 2025 · Requirements related to complying with good manufacturing practices.
Resolved
TEVA-LETROZOLE
2.5MG · TABLET · TEVA CANADA LIMITED
DIN 02343657 · ended Mar 10, 2025 · Disruption of the manufacture of the drug.
Resolved
SANDOZ LETROZOLE
2.5MG · TABLET · SANDOZ CANADA INCORPORATED
DIN 02344815 · ended Mar 3, 2025 · Delay in shipping of the drug.
Resolved
APO-LETROZOLE
2.5MG · TABLET · APOTEX INC
DIN 02358514 · ended Nov 7, 2024 · Disruption of the manufacture of the drug.
Resolved
TEVA-LETROZOLE
2.5MG · TABLET · TEVA CANADA LIMITED
DIN 02343657 · ended Sep 10, 2024 · Disruption of the manufacture of the drug.
Resolved
APO-LETROZOLE
2.5MG · TABLET · APOTEX INC
DIN 02358514 · ended Sep 5, 2024 · Disruption of the manufacture of the drug.

Showing 12 of 31 reports. All reports are on file with Health Canada.

What's happening

Letrozole is currently affected by an active shortage report filed with Health Canada by SIVEM PHARMACEUTICALS ULC.

The reported cause is: disruption of the manufacture of the drug. Manufacturers must report shortages, but end-date estimates are their own projections and often move.

If your usual product is affected, a pharmacist is the fastest route to a solution: they can dispense an unaffected manufacturer's equivalent when one exists, and in most provinces can adapt doses or substitute a therapeutic alternative without a new appointment.

Letrozole is classified under “HORMONE ANTAGONISTS AND RELATED AGENTS” (ATC L02BG).

Recent changes

Common questions

What is Letrozole used for?

An aromatase inhibitor used to treat hormone receptor positive breast cancer.

When will Letrozole be back in stock in Canada?

Manufacturers have not provided a reliable end date. This page updates automatically as soon as an estimate is filed.

Why is Letrozole in shortage?

See the reports above; manufacturers must state a reason (most commonly manufacturing disruption or a surge in demand) when filing with Health Canada.

What can my pharmacist do about it?

Often quite a lot: substitute an equivalent product from an unaffected manufacturer, adjust quantities, or in most provinces adapt or renew prescriptions on the spot. Call your pharmacy before visiting, and call 811 for free health advice.

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Possible alternatives in the same class (hormone antagonists and related agents)

Drugs in the same therapeutic class, best-supplied first. These are not automatic substitutes: only your pharmacist or prescriber can judge whether a switch makes sense for you.

Guides: what to do when your medication is in shortage · how to read shortage reports

Data reflects reports manufacturers are legally required to file with Health Canada, republished with per-drug aggregation by rxstat. Estimated end dates are supplied by manufacturers and frequently change. This page describes drug supply only and is not medical advice; never stop or switch a medication without speaking to your pharmacist or prescriber.