Source: Health Canada shortage reports · Updated Jul 23, 2026
Some Leflunomide products are in shortage in Canada (3 of 15 reported products), while others remain available. Your pharmacy may be able to substitute an unaffected manufacturer. The latest estimate for affected products to return is Aug 14, 2026.
A disease-modifying medication used to treat rheumatoid arthritis.
Products affected
3 / 15
In shortage since
Apr 21, 2026
Est. full return
Aug 14, 2026
Reports on file
55
Talk to a pharmacist
Pharmacists can substitute an unaffected manufacturer's version, adjust strengths, and in most provinces adapt or renew a prescription on the spot.
Independent services, not affiliated with rxstat; referral fees may apply. Free options exist depending on your province. In an emergency call 911; free health advice at 811.
Shortage history
Shortage history (red bands = periods in shortage).
Reports by product
The DIN is printed on your prescription label.
Active shortage
APO-LEFLUNOMIDE
10MG · TABLET · APOTEX INC
DIN 02256495 · since Apr 21, 2026, est. end Aug 7, 2026 · Disruption of the manufacture of the drug.
Active shortage
APO-LEFLUNOMIDE
20MG · TABLET · APOTEX INC
DIN 02256509 · since Jun 23, 2026, est. end Aug 7, 2026 · Disruption of the manufacture of the drug.
Active shortage
SANDOZ LEFLUNOMIDE
20MG · TABLET · SANDOZ CANADA INCORPORATED
DIN 02283972 · since Jun 22, 2026, est. end Aug 14, 2026 · Disruption of the manufacture of the drug.
Anticipated
SANDOZ LEFLUNOMIDE
10MG · TABLET · SANDOZ CANADA INCORPORATED
DIN 02283964 · Demand increase for the drug.
Resolved
TEVA-LEFLUNOMIDE
20MG · TABLET · TEVA CANADA LIMITED
DIN 02261278 · ended Mar 18, 2026 · Disruption of the manufacture of the drug.
Resolved
TEVA-LEFLUNOMIDE
10MG · TABLET · TEVA CANADA LIMITED
DIN 02261251 · ended Jun 3, 2026 · Disruption of the manufacture of the drug.
Resolved
TEVA-LEFLUNOMIDE
10MG · TABLET · TEVA CANADA LIMITED
DIN 02261251 · ended Mar 10, 2026 · Disruption of the manufacture of the drug.
Resolved
SANDOZ LEFLUNOMIDE
10MG · TABLET · SANDOZ CANADA INCORPORATED
DIN 02283964 · ended Jan 8, 2026 · Delay in shipping of the drug.
To be discontinued
ARAVA
10MG · TABLET · SANOFI-AVENTIS CANADA INC
DIN 02241888
To be discontinued
ARAVA
20MG · TABLET · SANOFI-AVENTIS CANADA INC
DIN 02241889
Resolved
ARAVA
20MG · TABLET · SANOFI-AVENTIS CANADA INC
DIN 02241889 · ended Jul 30, 2025
Resolved
APO-LEFLUNOMIDE
20MG · TABLET · APOTEX INC
DIN 02256509 · ended May 30, 2024 · Disruption of the manufacture of the drug.
Showing 12 of 55 reports. All reports are on file with Health Canada.
What's happening
Leflunomide is currently affected by 3 active shortage reports filed with Health Canada by APOTEX INC, SANDOZ CANADA INCORPORATED.
The reported cause is: disruption of the manufacture of the drug. Manufacturers must report shortages, but end-date estimates are their own projections and often move.
If your usual product is affected, a pharmacist is the fastest route to a solution: they can dispense an unaffected manufacturer's equivalent when one exists, and in most provinces can adapt doses or substitute a therapeutic alternative without a new appointment.
Recent changes
Jul 23, 2026
Estimated end date pushed back : Jul 24, 2026 → Aug 7, 2026
Jul 23, 2026
Estimated end date pushed back : Jul 24, 2026 → Aug 7, 2026
Jul 16, 2026
Estimated end date pushed back : Jul 17, 2026 → Jul 24, 2026
Jul 13, 2026
Estimated end date pushed back : Jul 17, 2026 → Aug 14, 2026
Jul 13, 2026
New report filed
Common questions
What is Leflunomide used for?
A disease-modifying medication used to treat rheumatoid arthritis.
When will Leflunomide be back in stock in Canada?
The latest manufacturer estimate is Aug 14, 2026. Estimates are self-reported and often slip; this page updates automatically when they change.
Why is Leflunomide in shortage?
See the reports above; manufacturers must state a reason (most commonly manufacturing disruption or a surge in demand) when filing with Health Canada.
What can my pharmacist do about it?
Often quite a lot: substitute an equivalent product from an unaffected manufacturer, adjust quantities, or in most provinces adapt or renew prescriptions on the spot. Call your pharmacy before visiting, and call 811 for free health advice.
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Possible alternatives in the same class
Drugs in the same therapeutic class, best-supplied first. These are not automatic substitutes: only your pharmacist or prescriber can judge whether a switch makes sense for you.
Data reflects reports manufacturers are legally required to file with Health Canada, republished with per-drug aggregation by rxstat. Estimated end dates are supplied by manufacturers and frequently change. This page describes drug supply only and is not medical advice; never stop or switch a medication without speaking to your pharmacist or prescriber.