rxstat › Shortages › Isosorbide-5-mononitrate
Isosorbide-5-mononitrate shortage status
Partial shortage
Source: Health Canada shortage reports · Updated Jul 9, 2026
Some Isosorbide-5-mononitrate products are in shortage in Canada (1 of 5 reported products), while others remain available. Your pharmacy may be able to substitute an unaffected manufacturer. The latest estimate for affected products to return is Nov 26, 2026.
In shortage since
Sep 29, 2023
Est. full return
Nov 26, 2026
Talk to your pharmacist. Pharmacists can often substitute another manufacturer's version, a different strength, or (in most provinces) adapt or renew a prescription on the spot. Your free provincial health line is 811.
Reports by product
Active shortagePMS-ISMN
60MG · TABLET (EXTENDED-RELEASE) · PHARMASCIENCE INC
DIN 02301288 · since Nov 24, 2023, est. end Nov 18, 2026 · Disruption of the manufacture of the drug.
Active shortagePMS-ISMN
60MG · TABLET (EXTENDED-RELEASE) · PHARMASCIENCE INC
DIN 02301288 · since Sep 29, 2023, est. end Nov 26, 2026 · Disruption of the manufacture of the drug.
ResolvedAPO-ISMN
60MG · TABLET (EXTENDED-RELEASE) · APOTEX INC
DIN 02272830 · ended May 29, 2025 · Disruption of the manufacture of the drug.
ResolvedPRO-ISMN - 60
60MG · TABLET (EXTENDED-RELEASE) · PRO DOC LIMITEE
DIN 02311321 · ended Jan 21, 2025 · Disruption of the manufacture of the drug.
DiscontinuedIMDUR
60MG · TABLET (EXTENDED-RELEASE) · JUNO PHARMACEUTICALS CORP.
DIN 02126559
DiscontinuedIMDUR
60MG · TABLET (EXTENDED-RELEASE) · JUNO PHARMACEUTICALS CORP.
DIN 02126559
ResolvedPMS-ISMN
60MG · TABLET (EXTENDED-RELEASE) · PHARMASCIENCE INC
DIN 02301288 · ended Aug 10, 2023 · Disruption of the manufacture of the drug.
ResolvedIMDUR - EXTENDED RELEASE TABLETS 60 MG
60MG · TABLET (EXTENDED-RELEASE) · JUNO PHARMACEUTICALS CORP.
DIN 02126559 · ended Dec 21, 2022 · Disruption of the manufacture of the drug.
ResolvedIMDUR
60MG · TABLET (EXTENDED-RELEASE) · JUNO PHARMACEUTICALS CORP.
DIN 02126559 · ended Dec 21, 2022 · Disruption of the manufacture of the drug.
ResolvedAPO-ISMN
60MG · TABLET (EXTENDED-RELEASE) · APOTEX INC
DIN 02272830 · ended Mar 24, 2020 · Disruption of the manufacture of the drug.
ResolvedPMS-ISMN
60MG · TABLET (EXTENDED-RELEASE) · PHARMASCIENCE INC
DIN 02301288 · ended Sep 9, 2019 · Disruption of the manufacture of the drug.
AvoidedPMS-ISMN
60MG · TABLET (EXTENDED-RELEASE) · PHARMASCIENCE INC
DIN 02301288 · ended Aug 19, 2018 · Disruption of the manufacture of the drug.
Showing 12 of 27 reports. All reports are on file with Health Canada.
What's happening
Isosorbide-5-mononitrate is currently affected by an active shortage report filed with Health Canada by PHARMASCIENCE INC.
The reported cause is: disruption of the manufacture of the drug. Manufacturers must report shortages, but end-date estimates are their own projections and often move.
If your usual product is affected, a pharmacist is the fastest route to a solution: they can dispense an unaffected manufacturer's equivalent when one exists, and in most provinces can adapt doses or substitute a therapeutic alternative without a new appointment.
Isosorbide-5-mononitrate is classified under “VASODILATORS USED IN CARDIAC DISEASES” (ATC C01DA).
Recent changes
Common questions
When will Isosorbide-5-mononitrate be back in stock in Canada?
The latest manufacturer estimate is Nov 26, 2026. Estimates are self-reported and often slip; this page updates automatically when they change.
Why is Isosorbide-5-mononitrate in shortage?
See the reports above; manufacturers must state a reason (most commonly manufacturing disruption or a surge in demand) when filing with Health Canada.
What can my pharmacist do about it?
Often quite a lot: substitute an equivalent product from an unaffected manufacturer, adjust quantities, or in most provinces adapt or renew prescriptions on the spot. Call your pharmacy before visiting, and call 811 for free health advice.
Guides: what to do when your medication is in shortage · how to read shortage reports
Data reflects reports manufacturers are legally required to file with Health Canada, republished with per-drug aggregation by rxstat. Estimated end dates are supplied by manufacturers and frequently change. This page describes drug supply only and is not medical advice; never stop or switch a medication without speaking to your pharmacist or prescriber.