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Immunoglobulin (Hizentra, Gammagard S/D) shortage status

Partial shortage

Source: Health Canada shortage reports · Updated Sep 16, 2026

Also sold as: Hizentra, Gammagard S/D, Gammagard, Cuvitru

Some Immunoglobulin products are in shortage in Canada (1 of 4 reported products), while others remain available. Your pharmacy may be able to substitute an unaffected manufacturer.

Concentrated antibodies used to treat immune deficiencies and certain autoimmune conditions.

Products affected
1 / 4
Reports on file
5
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Pharmacists can substitute an unaffected manufacturer's version, adjust strengths, and in most provinces adapt or renew a prescription on the spot.
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Shortage history

2023 2024 2025 2026

Shortage history (red bands = periods in shortage).

Reports by product

The DIN is printed on your prescription label.

Active shortage
HIZENTRA
200MG · SOLUTION · CSL BEHRING CANADA INC
DIN 02463067 · since ?, est. end Sep 16, 2026 · Disruption of the manufacture of the drug.
Resolved
GAMMAGARD S/D
5G · KIT SOLUTION POWDER FOR SOLUTION · TAKEDA CANADA INC
DIN 02231470 · ended Jan 29, 2024 · Shortage related to the disruption in supply of co-packaged sterile Water for Injection and not related to the immunoglobulin drug product.
Resolved
GAMMAGARD S/D
5G · KIT SOLUTION POWDER FOR SOLUTION · TAKEDA CANADA INC
DIN 02231470 · ended Sep 13, 2023 · Delay in shipping of the drug.
Resolved
GAMMAGARD LIQUID
10% · SOLUTION · SHIRE PHARMA CANADA ULC
DIN 02279444 · ended Jan 13, 2020 · Temporary shortage in some product size formats. Resolved as of 13Jan2020
Resolved
CUVITRU
200MG · SOLUTION · SHIRE PHARMA CANADA ULC
DIN 02461692 · ended Aug 23, 2019 · Demand increase for the drug.

What's happening

Immunoglobulin is currently affected by an active shortage report filed with Health Canada by CSL BEHRING CANADA INC.

The reported cause is: disruption of the manufacture of the drug. Manufacturers must report shortages, but end-date estimates are their own projections and often move.

If your usual product is affected, a pharmacist is the fastest route to a solution: they can dispense an unaffected manufacturer's equivalent when one exists, and in most provinces can adapt doses or substitute a therapeutic alternative without a new appointment.

Immunoglobulin is classified under “IMMUNOGLOBULINS” (ATC J06BA).

Recent changes

Common questions

What is Immunoglobulin used for?

Concentrated antibodies used to treat immune deficiencies and certain autoimmune conditions.

When will Immunoglobulin be back in stock in Canada?

Manufacturers have not provided a reliable end date. This page updates automatically as soon as an estimate is filed.

Why is Immunoglobulin in shortage?

See the reports above; manufacturers must state a reason (most commonly manufacturing disruption or a surge in demand) when filing with Health Canada.

What can my pharmacist do about it?

Often quite a lot: substitute an equivalent product from an unaffected manufacturer, adjust quantities, or in most provinces adapt or renew prescriptions on the spot. Call your pharmacy before visiting, and call 811 for free health advice.

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Possible alternatives in the same class (immunoglobulins)

Drugs in the same therapeutic class, best-supplied first. These are not automatic substitutes: only your pharmacist or prescriber can judge whether a switch makes sense for you.

Nirsevimab (Beyfortus) No current shortage group 0263541 (Evusheld) Discontinued 0 of 1 reported products affected

Guides: what to do when your medication is in shortage · how to read shortage reports

Data reflects reports manufacturers are legally required to file with Health Canada, republished with per-drug aggregation by rxstat. Estimated end dates are supplied by manufacturers and frequently change. This page describes drug supply only and is not medical advice; never stop or switch a medication without speaking to your pharmacist or prescriber.