rxstatShortages › Hepatitis B Surface Antigen A Virus / Inactivated

Hepatitis B Surface Antigen A Virus / Inactivated (Twinrix Junior, Twinrix) shortage status

Partial shortage

Source: Health Canada shortage reports · Updated Jul 9, 2026

Some Hepatitis B Surface Antigen A Virus / Inactivated products are in shortage in Canada (1 of 2 reported products), while others remain available. Your pharmacy may be able to substitute an unaffected manufacturer.

A combined vaccine used to protect against hepatitis A and hepatitis B.

Products affected
1 / 2
In shortage since
May 15, 2026
Reports on file
12
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Pharmacists can substitute an unaffected manufacturer's version, adjust strengths, and in most provinces adapt or renew a prescription on the spot.
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Shortage history

2023 2024 2025 2026

Shortage history (red bands = periods in shortage).

Reports by product

The DIN is printed on your prescription label.

Active shortage
TWINRIX JUNIOR
10MCG 360UNIT · SUSPENSION · GLAXOSMITHKLINE INC
DIN 02237548 · since May 15, 2026, est. end Jun 15, 2026 · Delay in shipping of the drug.
Resolved
TWINRIX JUNIOR
360UNIT 10MCG · SUSPENSION · GLAXOSMITHKLINE INC
DIN 02237548 · ended Dec 8, 2022 · Delay in shipping of the drug.
Resolved
TWINRIX
720UNIT 20MCG · SUSPENSION · GLAXOSMITHKLINE INC
DIN 02230578 · ended Mar 24, 2020 · Delay in shipping of the drug.
Resolved
TWINRIX
720UNIT 20MCG · SUSPENSION · GLAXOSMITHKLINE INC
DIN 02230578 · ended Oct 21, 2019 · Disruption of the manufacture of the drug.
Resolved
TWINRIX JUNIOR
360UNIT 10MCG · SUSPENSION · GLAXOSMITHKLINE INC
DIN 02237548 · ended May 10, 2019 · Demand increase for the drug.
Resolved
TWINRIX
720UNIT 20MCG · SUSPENSION · GLAXOSMITHKLINE INC
DIN 02230578 · ended Mar 14, 2019 · Demand increase for the drug.
Resolved
TWINRIX JUNIOR
360UNIT 10MCG · SUSPENSION · GLAXOSMITHKLINE INC
DIN 02237548 · ended Feb 6, 2019 · Demand increase for the drug.
Resolved
TWINRIX
720UNIT 20MCG · SUSPENSION · GLAXOSMITHKLINE INC
DIN 02230578 · ended Jan 17, 2018 · Demand increase for the drug.
Resolved
TWINRIX JUNIOR
360UNIT 10MCG · SUSPENSION · GLAXOSMITHKLINE INC
DIN 02237548 · ended Dec 4, 2017 · Demand increase for the drug.
Resolved
TWINRIX
720UNIT 20MCG · SUSPENSION · GLAXOSMITHKLINE INC
DIN 02230578 · ended Dec 4, 2017 · Delay in shipping of the drug.
Resolved
TWINRIX JUNIOR
360UNIT 10MCG · SUSPENSION · GLAXOSMITHKLINE INC
DIN 02237548 · ended Oct 10, 2017 · Delay in shipping of the drug.
Resolved
TWINRIX
720UNIT 20MCG · SUSPENSION · GLAXOSMITHKLINE INC
DIN 02230578 · ended Jul 10, 2017 · Demand increase for the drug.

What's happening

Hepatitis B Surface Antigen A Virus / Inactivated is currently affected by an active shortage report filed with Health Canada by GLAXOSMITHKLINE INC.

The reported cause is: delay in shipping of the drug. Manufacturers must report shortages, but end-date estimates are their own projections and often move.

If your usual product is affected, a pharmacist is the fastest route to a solution: they can dispense an unaffected manufacturer's equivalent when one exists, and in most provinces can adapt doses or substitute a therapeutic alternative without a new appointment.

Hepatitis B Surface Antigen A Virus / Inactivated is classified under “VIRAL VACCINES” (ATC J07BC).

Recent changes

Common questions

What is Hepatitis B Surface Antigen A Virus / Inactivated used for?

A combined vaccine used to protect against hepatitis A and hepatitis B.

When will Hepatitis B Surface Antigen A Virus / Inactivated be back in stock in Canada?

Manufacturers have not provided a reliable end date. This page updates automatically as soon as an estimate is filed.

Why is Hepatitis B Surface Antigen A Virus / Inactivated in shortage?

See the reports above; manufacturers must state a reason (most commonly manufacturing disruption or a surge in demand) when filing with Health Canada.

What can my pharmacist do about it?

Often quite a lot: substitute an equivalent product from an unaffected manufacturer, adjust quantities, or in most provinces adapt or renew prescriptions on the spot. Call your pharmacy before visiting, and call 811 for free health advice.

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Possible alternatives in the same class (viral vaccines)

Drugs in the same therapeutic class, best-supplied first. These are not automatic substitutes: only your pharmacist or prescriber can judge whether a switch makes sense for you.

Guides: what to do when your medication is in shortage · how to read shortage reports

Data reflects reports manufacturers are legally required to file with Health Canada, republished with per-drug aggregation by rxstat. Estimated end dates are supplied by manufacturers and frequently change. This page describes drug supply only and is not medical advice; never stop or switch a medication without speaking to your pharmacist or prescriber.