rxstatShortages › Estradiol Norethindrone

Estradiol Norethindrone (Estalis) shortage status

Shortage anticipated

Source: Health Canada shortage reports · Updated Jul 16, 2026

A shortage of Estradiol Norethindrone is anticipated but not yet confirmed. 1 product(s) have anticipated-shortage reports on file with Health Canada.

A combined hormone therapy used to relieve menopausal symptoms.

Products affected
0 / 2
Reports on file
19

Shortage history

2023 2024 2025 2026

Shortage history (red bands = periods in shortage).

Reports by product

The DIN is printed on your prescription label.

Anticipated
ESTALIS 140/50 MCG
140MCG 50MCG · PATCH · SANDOZ CANADA INCORPORATED
DIN 02241835 · Demand increase for the drug.
Resolved
ESTALIS 250/50 MCG
50MCG 250MCG · PATCH · SANDOZ CANADA INCORPORATED
DIN 02241837 · ended Sep 19, 2025 · Disruption of the manufacture of the drug.
Resolved
ESTALIS 250/50 MCG
50MCG 250MCG · PATCH · SANDOZ CANADA INCORPORATED
DIN 02241837 · ended Aug 18, 2025 · Disruption of the manufacture of the drug.
Resolved
ESTALIS 140/50 MCG
140MCG 50MCG · PATCH · SANDOZ CANADA INCORPORATED
DIN 02241835 · ended Aug 1, 2025 · Disruption of the manufacture of the drug.
Resolved
ESTALIS 140/50 MCG
140MCG 50MCG · PATCH · SANDOZ CANADA INCORPORATED
DIN 02241835 · ended Dec 10, 2024 · Disruption of the manufacture of the drug.
Resolved
ESTALIS 250/50 MCG
250MCG 50MCG · PATCH · SANDOZ CANADA INCORPORATED
DIN 02241837 · ended Apr 23, 2024 · Disruption of the manufacture of the drug.
Resolved
ESTALIS 140/50 MCG
140MCG 50MCG · PATCH · SANDOZ CANADA INCORPORATED
DIN 02241835 · ended Feb 19, 2024 · Requirements related to complying with good manufacturing practices.
Resolved
ESTALIS 140/50 MCG
140MCG 50MCG · PATCH · SANDOZ CANADA INCORPORATED
DIN 02241835 · ended Nov 6, 2023 · Disruption of the manufacture of the drug.
Resolved
ESTALIS 250/50 MCG
250MCG 50MCG · PATCH · SANDOZ CANADA INCORPORATED
DIN 02241837 · ended Nov 6, 2023 · Disruption of the manufacture of the drug.
Resolved
ESTALIS 140/50 MCG
140MCG 50MCG · PATCH · SANDOZ CANADA INCORPORATED
DIN 02241835 · ended May 8, 2023 · Disruption of the manufacture of the drug.
Resolved
ESTALIS 140/50 MCG
140MCG 50MCG · PATCH · SANDOZ CANADA INCORPORATED
DIN 02241835 · ended Feb 24, 2023 · Delay in shipping of the drug.
Resolved
ESTALIS 140/50 MCG
140MCG 50MCG · PATCH · NOVARTIS PHARMACEUTICALS CANADA INC
DIN 02241835 · ended Sep 9, 2022 · Delay in shipping of the drug.

Showing 12 of 19 reports. All reports are on file with Health Canada.

What's happening

A manufacturer has told Health Canada it expects supply of Estradiol Norethindrone to fall short of demand. Anticipated shortages sometimes resolve without patients noticing; this page updates as soon as the status changes.

Estradiol Norethindrone is classified under “PROGESTOGENS AND ESTROGENS IN COMBINATION” (ATC G03FA).

Recent changes

Common questions

What is Estradiol Norethindrone used for?

A combined hormone therapy used to relieve menopausal symptoms.

When will Estradiol Norethindrone be back in stock in Canada?

Manufacturers have not provided a reliable end date. This page updates automatically as soon as an estimate is filed.

Why is Estradiol Norethindrone in shortage?

See the reports above; manufacturers must state a reason (most commonly manufacturing disruption or a surge in demand) when filing with Health Canada.

What can my pharmacist do about it?

Often quite a lot: substitute an equivalent product from an unaffected manufacturer, adjust quantities, or in most provinces adapt or renew prescriptions on the spot. Call your pharmacy before visiting, and call 811 for free health advice.

Email alerts

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Possible alternatives in the same class (progestogens and estrogens in combination)

Drugs in the same therapeutic class, best-supplied first. These are not automatic substitutes: only your pharmacist or prescriber can judge whether a switch makes sense for you.

Guides: what to do when your medication is in shortage · how to read shortage reports

Data reflects reports manufacturers are legally required to file with Health Canada, republished with per-drug aggregation by rxstat. Estimated end dates are supplied by manufacturers and frequently change. This page describes drug supply only and is not medical advice; never stop or switch a medication without speaking to your pharmacist or prescriber.