Source: Health Canada shortage reports · Updated Jul 9, 2026
Some Doxylamine Pyridoxine products are in shortage in Canada (1 of 2 reported products), while others remain available. Your pharmacy may be able to substitute an unaffected manufacturer.
A combination of an antihistamine and vitamin B6 used to treat nausea and vomiting of pregnancy.
Products affected
1 / 2
In shortage since
Jun 2, 2026
Reports on file
14
Talk to a pharmacist
Pharmacists can substitute an unaffected manufacturer's version, adjust strengths, and in most provinces adapt or renew a prescription on the spot.
Independent services, not affiliated with rxstat; referral fees may apply. Free options exist depending on your province. In an emergency call 911; free health advice at 811.
Shortage history
Shortage history (red bands = periods in shortage).
Reports by product
The DIN is printed on your prescription label.
Active shortage
APO-DOXYLAMINE/B6
10MG
10MG · TABLET (DELAYED-RELEASE) · APOTEX INC
DIN 02413248 · since Jun 2, 2026, est. end Jul 3, 2026 · Disruption of the manufacture of the drug.
Resolved
APO-DOXYLAMINE/B6
10MG
10MG · TABLET (DELAYED-RELEASE) · APOTEX INC
DIN 02413248 · ended Jan 2, 2025 · Disruption of the manufacture of the drug.
Resolved
APO-DOXYLAMINE/B6
10MG
10MG · TABLET (DELAYED-RELEASE) · APOTEX INC
DIN 02413248 · ended Oct 17, 2024 · Disruption of the manufacture of the drug.
Resolved
APO-DOXYLAMINE/B6
10MG
10MG · TABLET (DELAYED-RELEASE) · APOTEX INC
DIN 02413248 · ended Mar 21, 2024 · Disruption of the manufacture of the drug.
Resolved
APO-DOXYLAMINE/B6
10MG
10MG · TABLET (DELAYED-RELEASE) · APOTEX INC
DIN 02413248 · ended Feb 8, 2024 · Disruption of the manufacture of the drug.
Resolved
APO-DOXYLAMINE/B6
10MG
10MG · TABLET (DELAYED-RELEASE) · APOTEX INC
DIN 02413248 · ended Feb 8, 2024 · Disruption of the manufacture of the drug.
DIN 02406187 · ended Sep 21, 2023 · Disruption of the manufacture of the drug.
Resolved
APO-DOXYLAMINE/B6
10MG
10MG · TABLET (DELAYED-RELEASE) · APOTEX INC
DIN 02413248 · ended Apr 12, 2022 · Disruption of the manufacture of the drug.
Resolved
APO-DOXYLAMINE/B6
10MG
10MG · TABLET (DELAYED-RELEASE) · APOTEX INC
DIN 02413248 · ended Oct 30, 2020 · Disruption of the manufacture of the drug.
Resolved
APO-DOXYLAMINE/B6
10MG
10MG · TABLET (DELAYED-RELEASE) · APOTEX INC
DIN 02413248 · ended May 2, 2019 · Disruption of the manufacture of the drug.
Resolved
APO-DOXYLAMINE/B6
10MG
10MG · TABLET (DELAYED-RELEASE) · APOTEX INC
DIN 02413248 · ended May 2, 2019 · Disruption of the manufacture of the drug.
Showing 12 of 14 reports. All reports are on file with Health Canada.
What's happening
Doxylamine Pyridoxine is currently affected by an active shortage report filed with Health Canada by APOTEX INC.
The reported cause is: disruption of the manufacture of the drug. Manufacturers must report shortages, but end-date estimates are their own projections and often move.
If your usual product is affected, a pharmacist is the fastest route to a solution: they can dispense an unaffected manufacturer's equivalent when one exists, and in most provinces can adapt doses or substitute a therapeutic alternative without a new appointment.
Doxylamine Pyridoxine is classified under “ANTIHISTAMINES FOR SYSTEMIC USE” (ATC R06AA).
Recent changes
No changes recorded yet.
Common questions
What is Doxylamine Pyridoxine used for?
A combination of an antihistamine and vitamin B6 used to treat nausea and vomiting of pregnancy.
When will Doxylamine Pyridoxine be back in stock in Canada?
Manufacturers have not provided a reliable end date. This page updates automatically as soon as an estimate is filed.
Why is Doxylamine Pyridoxine in shortage?
See the reports above; manufacturers must state a reason (most commonly manufacturing disruption or a surge in demand) when filing with Health Canada.
What can my pharmacist do about it?
Often quite a lot: substitute an equivalent product from an unaffected manufacturer, adjust quantities, or in most provinces adapt or renew prescriptions on the spot. Call your pharmacy before visiting, and call 811 for free health advice.
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Drugs in the same therapeutic class, best-supplied first. These are not automatic substitutes: only your pharmacist or prescriber can judge whether a switch makes sense for you.
Data reflects reports manufacturers are legally required to file with Health Canada, republished with per-drug aggregation by rxstat. Estimated end dates are supplied by manufacturers and frequently change. This page describes drug supply only and is not medical advice; never stop or switch a medication without speaking to your pharmacist or prescriber.