Source: Health Canada shortage reports · Updated Jul 9, 2026
Some Doxepin products are in shortage in Canada (1 of 11 reported products), while others remain available. Your pharmacy may be able to substitute an unaffected manufacturer.
A tricyclic antidepressant used to treat depression and anxiety, and in low doses for insomnia.
Products affected
1 / 11
In shortage since
Mar 10, 2017
Reports on file
26
Talk to a pharmacist
Pharmacists can substitute an unaffected manufacturer's version, adjust strengths, and in most provinces adapt or renew a prescription on the spot.
Independent services, not affiliated with rxstat; referral fees may apply. Free options exist depending on your province. In an emergency call 911; free health advice at 811.
Shortage history
Shortage history (red bands = periods in shortage).
Reports by product
The DIN is printed on your prescription label.
Active shortage
APO-DOXEPIN
150MG · CAPSULE · APOTEX INC
DIN 02050056 · since Mar 10, 2017, no end estimate · Disruption of the manufacture of the drug.
Resolved
SINEQUAN
25MG · CAPSULE · AA PHARMA INC
DIN 00024333 · ended Dec 16, 2025 · Disruption of the manufacture of the drug.
Resolved
SINEQUAN
75MG · CAPSULE · AA PHARMA INC
DIN 00400750 · ended Dec 16, 2025 · Disruption of the manufacture of the drug.
Resolved
SINEQUAN
25MG · CAPSULE · AA PHARMA INC
DIN 00024333 · ended Sep 16, 2025 · Disruption of the manufacture of the drug.
Resolved
SINEQUAN
100MG · CAPSULE · AA PHARMA INC
DIN 00326925 · ended Sep 16, 2025 · Disruption of the manufacture of the drug.
Resolved
SINEQUAN
10MG · CAPSULE · AA PHARMA INC
DIN 00024325 · ended Jan 15, 2025 · Disruption of the manufacture of the drug.
Resolved
SINEQUAN
10MG · CAPSULE · AA PHARMA INC
DIN 00024325 · ended Sep 4, 2024 · Disruption of the manufacture of the drug.
Resolved
SINEQUAN
10MG · CAPSULE · AA PHARMA INC
DIN 00024325 · ended Apr 28, 2023 · Disruption of the manufacture of the drug.
Resolved
SINEQUAN
10MG · CAPSULE · AA PHARMA INC
DIN 00024325 · ended Nov 28, 2022 · Disruption of the manufacture of the drug.
Resolved
SINEQUAN
75MG · CAPSULE · AA PHARMA INC
DIN 00400750 · ended Nov 28, 2022 · Disruption of the manufacture of the drug.
Resolved
SINEQUAN
25MG · CAPSULE · AA PHARMA INC
DIN 00024333 · ended Nov 28, 2022 · Disruption of the manufacture of the drug.
Resolved
SINEQUAN
50MG · CAPSULE · AA PHARMA INC
DIN 00024341 · ended Nov 28, 2022 · Disruption of the manufacture of the drug.
Showing 12 of 26 reports. All reports are on file with Health Canada.
What's happening
Doxepin is currently affected by an active shortage report filed with Health Canada by APOTEX INC.
The reported cause is: disruption of the manufacture of the drug. Manufacturers must report shortages, but end-date estimates are their own projections and often move.
If your usual product is affected, a pharmacist is the fastest route to a solution: they can dispense an unaffected manufacturer's equivalent when one exists, and in most provinces can adapt doses or substitute a therapeutic alternative without a new appointment.
Doxepin is classified under “ANTIDEPRESSANTS” (ATC N06AA).
Recent changes
No changes recorded yet.
Common questions
What is Doxepin used for?
A tricyclic antidepressant used to treat depression and anxiety, and in low doses for insomnia.
When will Doxepin be back in stock in Canada?
Manufacturers have not provided a reliable end date. This page updates automatically as soon as an estimate is filed.
Why is Doxepin in shortage?
See the reports above; manufacturers must state a reason (most commonly manufacturing disruption or a surge in demand) when filing with Health Canada.
What can my pharmacist do about it?
Often quite a lot: substitute an equivalent product from an unaffected manufacturer, adjust quantities, or in most provinces adapt or renew prescriptions on the spot. Call your pharmacy before visiting, and call 811 for free health advice.
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Drugs in the same therapeutic class, best-supplied first. These are not automatic substitutes: only your pharmacist or prescriber can judge whether a switch makes sense for you.
Data reflects reports manufacturers are legally required to file with Health Canada, republished with per-drug aggregation by rxstat. Estimated end dates are supplied by manufacturers and frequently change. This page describes drug supply only and is not medical advice; never stop or switch a medication without speaking to your pharmacist or prescriber.