rxstat › Shortages › Dinoprostone

Dinoprostone (Prostin E2, Prepidil) shortage status

Discontinued

Source: Health Canada shortage reports · Updated Jul 27, 2026

Dinoprostone products have been discontinued in Canada. See the reports below for which products and when.

A prostaglandin used to help induce labour by ripening the cervix.

Products affected
0 / 4
Reports on file
11

Shortage history

2023 2024 2025 2026

Shortage history (red bands = periods in shortage).

Reports by product

The DIN is printed on your prescription label.

Discontinued
PREPIDIL GEL
0.5MG · GEL · PFIZER CANADA ULC
DIN 00860786
Resolved
PROSTIN E2 TABLETS
0.5MG · TABLET · PFIZER CANADA ULC
DIN 00400688 · ended Jul 24, 2026 · Shortage of an active ingredient.
Resolved
PROSTIN E2 VAGINAL GEL
1MG · GEL · PFIZER CANADA ULC
DIN 01919679 · ended Jul 24, 2026 · Shortage of an active ingredient.
Resolved
PROSTIN E2 VAGINAL GEL
2MG · GEL · PFIZER CANADA ULC
DIN 01919687 · ended Jul 24, 2026 · Shortage of an active ingredient.
Resolved
PREPIDIL GEL
0.5MG · GEL · PFIZER CANADA ULC
DIN 00860786 · ended Jul 24, 2026 · Disruption of the manufacture of the drug.
To be discontinued
PROSTIN E2 VAGINAL GEL
2MG · GEL · PFIZER CANADA ULC
DIN 01919687
To be discontinued
PROSTIN E2 VAGINAL GEL
1MG · GEL · PFIZER CANADA ULC
DIN 01919679
To be discontinued
PROSTIN E2 TABLETS
0.5MG · TABLET · PFIZER CANADA ULC
DIN 00400688
Resolved
PROSTIN E2 TABLETS
0.5MG · TABLET · PFIZER CANADA ULC
DIN 00400688 · ended Oct 15, 2024 · Disruption of the manufacture of the drug.
Resolved
PREPIDIL GEL
0.5MG · GEL · PFIZER CANADA ULC
DIN 00860786 · ended May 7, 2021 · Disruption of the manufacture of the drug.
Resolved
PROSTIN E2 TABLETS
0.5MG · TABLET · PFIZER CANADA ULC
DIN 00400688 · ended Mar 25, 2020 · Disruption of the manufacture of the drug.

What's happening

One or more Dinoprostone products have been permanently discontinued by their manufacturers. If your product is affected, ask your pharmacist about equivalent products still on the market.

Dinoprostone is classified under “UTEROTONICS” (ATC G02AD).

Recent changes

Common questions

What is Dinoprostone used for?

A prostaglandin used to help induce labour by ripening the cervix.

When will Dinoprostone be back in stock in Canada?

Manufacturers have not provided a reliable end date. This page updates automatically as soon as an estimate is filed.

Why is Dinoprostone in shortage?

See the reports above; manufacturers must state a reason (most commonly manufacturing disruption or a surge in demand) when filing with Health Canada.

What can my pharmacist do about it?

Often quite a lot: substitute an equivalent product from an unaffected manufacturer, adjust quantities, or in most provinces adapt or renew prescriptions on the spot. Call your pharmacy before visiting, and call 811 for free health advice.

Email alerts

Get an email when this drug's status changes. Double opt-in, one-click unsubscribe.

Related drugs (uterotonics)

Dinoprost (Prostin F2 Alpha) Discontinued 0 of 1 reported products affected

Guides: what to do when your medication is in shortage · how to read shortage reports

Data reflects reports manufacturers are legally required to file with Health Canada, republished with per-drug aggregation by rxstat. Estimated end dates are supplied by manufacturers and frequently change. This page describes drug supply only and is not medical advice; never stop or switch a medication without speaking to your pharmacist or prescriber.