rxstat › Shortages › Darunavir

Darunavir (Prezista) shortage status

Partial shortage

Source: Health Canada shortage reports · Updated Oct 16, 2026

Some Darunavir products are in shortage in Canada (1 of 9 reported products), while others remain available. Your pharmacy may be able to substitute an unaffected manufacturer. The latest estimate for affected products to return is Dec 11, 2026.

An antiviral (protease inhibitor) used as part of combination therapy to treat HIV infection.

Products affected
1 / 9
In shortage since
Oct 13, 2026
Est. full return
Dec 11, 2026
Reports on file
14
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Shortage history

2023 2024 2025 2026

Shortage history (red bands = periods in shortage).

Reports by product

The DIN is printed on your prescription label.

Active shortage
APO-DARUNAVIR
800MG · TABLET · APOTEX INC
DIN 02487268 · since Oct 13, 2026, est. end Dec 11, 2026 · Disruption of the manufacture of the drug.
Resolved
APO-DARUNAVIR
800MG · TABLET · APOTEX INC
DIN 02487268 · ended Aug 20, 2026 · Disruption of the manufacture of the drug.
Resolved
APO-DARUNAVIR
600MG · TABLET · APOTEX INC
DIN 02487241 · ended Aug 20, 2026 · Disruption of the manufacture of the drug.
Resolved
AURO-DARUNAVIR
600MG · TABLET · AURO PHARMA INC
DIN 02486121 · ended Jan 27, 2025 · Demand increase for the drug.
Resolved
APO-DARUNAVIR
600MG · TABLET · APOTEX INC
DIN 02487241 · ended Oct 1, 2024 · Disruption of the manufacture of the drug.
Resolved
AURO-DARUNAVIR
800MG · TABLET · AURO PHARMA INC
DIN 02486148 · ended Jun 13, 2024 · Demand increase for the drug.
To be discontinued
PREZISTA
800MG · TABLET · JANSSEN INC
DIN 02393050
To be discontinued
PREZISTA
75MG · TABLET · JANSSEN INC
DIN 02338432
To be discontinued
PREZISTA
600MG · TABLET · JANSSEN INC
DIN 02324024
To be discontinued
PREZISTA
150MG · TABLET · JANSSEN INC
DIN 02369753
To be discontinued
PREZISTA
100MG · SUSPENSION · JANSSEN INC
DIN 02416530
Resolved
AURO-DARUNAVIR
600MG · TABLET · AURO PHARMA INC
DIN 02486121 · ended Jan 10, 2023 · Demand increase for the drug.

Showing 12 of 14 reports. All reports are on file with Health Canada.

What's happening

Darunavir is currently affected by an active shortage report filed with Health Canada by APOTEX INC.

The reported cause is: disruption of the manufacture of the drug. Manufacturers must report shortages, but end-date estimates are their own projections and often move.

If your usual product is affected, a pharmacist is the fastest route to a solution: they can dispense an unaffected manufacturer's equivalent when one exists, and in most provinces can adapt doses or substitute a therapeutic alternative without a new appointment.

Darunavir is classified under “DIRECT ACTING ANTIVIRALS” (ATC J05AE).

Recent changes

Common questions

What is Darunavir used for?

An antiviral (protease inhibitor) used as part of combination therapy to treat HIV infection.

When will Darunavir be back in stock in Canada?

The latest manufacturer estimate is Dec 11, 2026. Estimates are self-reported and often slip; this page updates automatically when they change.

Why is Darunavir in shortage?

See the reports above; manufacturers must state a reason (most commonly manufacturing disruption or a surge in demand) when filing with Health Canada.

What can my pharmacist do about it?

Often quite a lot: substitute an equivalent product from an unaffected manufacturer, adjust quantities, or in most provinces adapt or renew prescriptions on the spot. Call your pharmacy before visiting, and call 811 for free health advice.

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Possible alternatives in the same class (direct acting antivirals)

Drugs in the same therapeutic class, best-supplied first. These are not automatic substitutes: only your pharmacist or prescriber can judge whether a switch makes sense for you.

Entecavir (Baraclude) No current shortage Inosine Pranobex (Imunovir) No current shortage Letermovir (Prevymis) No current shortage Nirmatrelvir Ritonavir (Paxlovid) No current shortage Ritonavir (Norvir) No current shortage Adefovir Dipivoxil (Hepsera) Partial shortage 1 of 2 reported products affected

Guides: what to do when your medication is in shortage · how to read shortage reports

Data reflects reports manufacturers are legally required to file with Health Canada, republished with per-drug aggregation by rxstat. Estimated end dates are supplied by manufacturers and frequently change. This page describes drug supply only and is not medical advice; never stop or switch a medication without speaking to your pharmacist or prescriber.