rxstatShortages › Daptomycin

Daptomycin (Cubicin Rf) shortage status

Partial shortage

Source: Health Canada shortage reports · Updated Jul 9, 2026

Some Daptomycin products are in shortage in Canada (1 of 3 reported products), while others remain available. Your pharmacy may be able to substitute an unaffected manufacturer.

An antibiotic used to treat serious infections caused by certain gram-positive bacteria.

Products affected
1 / 3
In shortage since
Oct 23, 2023
Reports on file
8
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Pharmacists can substitute an unaffected manufacturer's version, adjust strengths, and in most provinces adapt or renew a prescription on the spot.
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Shortage history

2023 2024 2025 2026

Shortage history (red bands = periods in shortage).

Reports by product

The DIN is printed on your prescription label.

Active shortage
DAPTOMYCIN FOR INJECTION
500MG · POWDER FOR SOLUTION · ACCORD HEALTHCARE INC
DIN 02494590 · since Oct 23, 2023, no end estimate · Disruption of the manufacture of the drug.
Resolved
DAPTOMYCIN FOR INJECTION
500MG · POWDER FOR SOLUTION · SANDOZ CANADA INCORPORATED
DIN 02490838 · ended Mar 23, 2026 · Disruption of the manufacture of the drug.
To be discontinued
CUBICIN RF
500MG · POWDER FOR SOLUTION · CUBIST PHARMACEUTICALS LLC
DIN 02465493
Resolved
DAPTOMYCIN FOR INJECTION
500MG · POWDER FOR SOLUTION · SANDOZ CANADA INCORPORATED
DIN 02490838 · ended Nov 27, 2023 · Disruption of the manufacture of the drug.
Resolved
DAPTOMYCIN FOR INJECTION
500MG · POWDER FOR SOLUTION · SANDOZ CANADA INCORPORATED
DIN 02490838 · ended Jun 27, 2023 · Disruption of the manufacture of the drug.
Resolved
CUBICIN RF
500MG · POWDER FOR SOLUTION · CUBIST PHARMACEUTICALS LLC
DIN 02465493 · ended Nov 7, 2022 · Disruption of the manufacture of the drug.
Resolved
DAPTOMYCIN FOR INJECTION
500MG · POWDER FOR SOLUTION · SANDOZ CANADA INCORPORATED
DIN 02490838 · ended Jul 6, 2022 · Delay in shipping of the drug.
Resolved
DAPTOMYCIN FOR INJECTION
500MG · POWDER FOR SOLUTION · SANDOZ CANADA INCORPORATED
DIN 02490838 · ended Apr 20, 2022 · Disruption of the manufacture of the drug.

What's happening

Daptomycin is currently affected by an active shortage report filed with Health Canada by ACCORD HEALTHCARE INC.

The reported cause is: disruption of the manufacture of the drug. Manufacturers must report shortages, but end-date estimates are their own projections and often move.

If your usual product is affected, a pharmacist is the fastest route to a solution: they can dispense an unaffected manufacturer's equivalent when one exists, and in most provinces can adapt doses or substitute a therapeutic alternative without a new appointment.

Daptomycin is classified under “OTHER ANTIBACTERIALS” (ATC J01XX).

Recent changes

Common questions

What is Daptomycin used for?

An antibiotic used to treat serious infections caused by certain gram-positive bacteria.

When will Daptomycin be back in stock in Canada?

Manufacturers have not provided a reliable end date. This page updates automatically as soon as an estimate is filed.

Why is Daptomycin in shortage?

See the reports above; manufacturers must state a reason (most commonly manufacturing disruption or a surge in demand) when filing with Health Canada.

What can my pharmacist do about it?

Often quite a lot: substitute an equivalent product from an unaffected manufacturer, adjust quantities, or in most provinces adapt or renew prescriptions on the spot. Call your pharmacy before visiting, and call 811 for free health advice.

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Possible alternatives in the same class (other antibacterials)

Drugs in the same therapeutic class, best-supplied first. These are not automatic substitutes: only your pharmacist or prescriber can judge whether a switch makes sense for you.

Guides: what to do when your medication is in shortage · how to read shortage reports

Data reflects reports manufacturers are legally required to file with Health Canada, republished with per-drug aggregation by rxstat. Estimated end dates are supplied by manufacturers and frequently change. This page describes drug supply only and is not medical advice; never stop or switch a medication without speaking to your pharmacist or prescriber.