rxstat › Shortages › Chloride Thrombin Aprotinin Sealer Protein
Chloride Thrombin Aprotinin Sealer Protein (Tisseel, Artiss) shortage status
Widespread shortage
Source: Health Canada shortage reports · Updated Nov 5, 2026
Chloride Thrombin Aprotinin Sealer Protein is in a widespread shortage in Canada. 2 of 2 reported products are affected. The latest manufacturer estimate for full recovery is Mar 15, 2027.
Products affected
2 / 2
In shortage since
Oct 8, 2026
Est. full return
Mar 15, 2027
Reports on file
7
Talk to a pharmacist
Pharmacists can substitute an unaffected manufacturer's version, adjust strengths, and in most provinces adapt or renew a prescription on the spot.
Independent services, not affiliated with rxstat; referral fees may apply. Free options exist depending on your province. In an emergency call 911; free health advice at 811.
Shortage history
Shortage history (red bands = periods in shortage).
DIN 02326167 · ended Jul 19, 2022 · Delay in shipping of the drug.
What's happening
Chloride Thrombin Aprotinin Sealer Protein is currently affected by 2 active shortage reports filed with Health Canada by BAXTER CORPORATION.
The reported causes are: demand increase for the drug; delay in shipping of the drug. Manufacturers must report shortages, but end-date estimates are their own projections and often move.
If your usual product is affected, a pharmacist is the fastest route to a solution: they can dispense an unaffected manufacturer's equivalent when one exists, and in most provinces can adapt doses or substitute a therapeutic alternative without a new appointment.
Chloride Thrombin Aprotinin Sealer Protein is classified under “VITAMIN K AND OTHER HEMOSTATICS” (ATC B02BC).
Recent changes
Oct 27, 2026
New report filed
Oct 13, 2026
New report filed
Oct 13, 2026
New report filed
Oct 13, 2026
New report filed
Common questions
When will Chloride Thrombin Aprotinin Sealer Protein be back in stock in Canada?
The latest manufacturer estimate is Mar 15, 2027. Estimates are self-reported and often slip; this page updates automatically when they change.
Why is Chloride Thrombin Aprotinin Sealer Protein in shortage?
See the reports above; manufacturers must state a reason (most commonly manufacturing disruption or a surge in demand) when filing with Health Canada.
What can my pharmacist do about it?
Often quite a lot: substitute an equivalent product from an unaffected manufacturer, adjust quantities, or in most provinces adapt or renew prescriptions on the spot. Call your pharmacy before visiting, and call 811 for free health advice.
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Drugs in the same therapeutic class, best-supplied first. These are not automatic substitutes: only your pharmacist or prescriber can judge whether a switch makes sense for you.
Data reflects reports manufacturers are legally required to file with Health Canada, republished with per-drug aggregation by rxstat. Estimated end dates are supplied by manufacturers and frequently change. This page describes drug supply only and is not medical advice; never stop or switch a medication without speaking to your pharmacist or prescriber.