rxstat › Shortages › Brimonidine

Brimonidine (Alphagan P, Alphagan) shortage status

Partial shortage

Source: Health Canada shortage reports · Updated Nov 5, 2026

Some Brimonidine products are in shortage in Canada (3 of 10 reported products), while others remain available. Your pharmacy may be able to substitute an unaffected manufacturer. The latest estimate for affected products to return is Feb 5, 2027.

An eye drop used to lower pressure inside the eye in glaucoma and ocular hypertension.

Products affected
3 / 10
In shortage since
Sep 8, 2026
Est. full return
Feb 5, 2027
Reports on file
51
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Shortage history

2023 2024 2025 2026

Shortage history (red bands = periods in shortage).

Reports by product

The DIN is printed on your prescription label.

Active shortage
BRIMONIDINE P
0.15% · SOLUTION · AA PHARMA INC
DIN 02301334 · since Nov 3, 2026, est. end Jan 29, 2027 · Disruption of the manufacture of the drug.
Active shortage
BRIMONIDINE P
0.15% · SOLUTION · AA PHARMA INC
DIN 02301334 · since Sep 8, 2026, est. end Nov 20, 2026 · Disruption of the manufacture of the drug.
Active shortage
JAMP BRIMONIDINE
0.2% · SOLUTION · JAMP PHARMA CORPORATION
DIN 02449226 · since Sep 15, 2026, est. end Feb 5, 2027 · Demand increase for the drug.
Active shortage
BRIMONIDINE
0.2% · SOLUTION · STERI-MED PHARMA INC.
DIN 02562316 · since Oct 1, 2026, no end estimate · Demand increase for the drug.
Resolved
BRIMONIDINE P
0.15% · SOLUTION · AA PHARMA INC
DIN 02301334 · ended Jul 2, 2026 · Disruption of the manufacture of the drug.
Resolved
BRIMONIDINE P
0.15% · SOLUTION · AA PHARMA INC
DIN 02301334 · ended Jul 2, 2026 · Disruption of the manufacture of the drug.
Resolved
ALPHAGAN
0.2% · SOLUTION LIQUID · ABBVIE CORPORATION
DIN 02236876 · ended Sep 10, 2026 · Demand increase for the drug.
Resolved
ALPHAGAN P
0.15% · SOLUTION · ABBVIE CORPORATION
DIN 02248151 · ended Sep 3, 2026 · Demand increase for the drug.
Resolved
JAMP BRIMONIDINE
0.2% · SOLUTION · JAMP PHARMA CORPORATION
DIN 02449226 · ended Jul 30, 2026 · Disruption of the manufacture of the drug.
Resolved
JAMP BRIMONIDINE
0.2% · SOLUTION · JAMP PHARMA CORPORATION
DIN 02449226 · ended May 12, 2026 · Increase in demand - Allocation
Resolved
SANDOZ BRIMONIDINE
0.2% · SOLUTION · SANDOZ CANADA INCORPORATED
DIN 02305429 · ended Mar 9, 2026 · Disruption of the manufacture of the drug.
Resolved
SANDOZ BRIMONIDINE
0.2% · SOLUTION · SANDOZ CANADA INCORPORATED
DIN 02305429 · ended Jan 30, 2026 · Disruption of the manufacture of the drug.

Showing 12 of 51 reports. All reports are on file with Health Canada.

What's happening

Brimonidine is currently affected by 3 active shortage reports filed with Health Canada by AA PHARMA INC, JAMP PHARMA CORPORATION, STERI-MED PHARMA INC..

The reported causes are: disruption of the manufacture of the drug; demand increase for the drug. Manufacturers must report shortages, but end-date estimates are their own projections and often move.

If your usual product is affected, a pharmacist is the fastest route to a solution: they can dispense an unaffected manufacturer's equivalent when one exists, and in most provinces can adapt doses or substitute a therapeutic alternative without a new appointment.

Brimonidine is classified under “ANTIGLAUCOMA PREPARATIONS AND MIOTICS” (ATC S01EA).

Recent changes

Common questions

What is Brimonidine used for?

An eye drop used to lower pressure inside the eye in glaucoma and ocular hypertension.

When will Brimonidine be back in stock in Canada?

The latest manufacturer estimate is Feb 5, 2027. Estimates are self-reported and often slip; this page updates automatically when they change.

Why is Brimonidine in shortage?

See the reports above; manufacturers must state a reason (most commonly manufacturing disruption or a surge in demand) when filing with Health Canada.

What can my pharmacist do about it?

Often quite a lot: substitute an equivalent product from an unaffected manufacturer, adjust quantities, or in most provinces adapt or renew prescriptions on the spot. Call your pharmacy before visiting, and call 811 for free health advice.

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Possible alternatives in the same class (antiglaucoma preparations and miotics)

Drugs in the same therapeutic class, best-supplied first. These are not automatic substitutes: only your pharmacist or prescriber can judge whether a switch makes sense for you.

Apraclonidine (Iopidine) No current shortage Dorzolamide (Trusopt) No current shortage Latanoprostene Bunod (Vyzulta) No current shortage Timolol Brinzolamide No current shortage Timolol Travoprost (Duotrav Pq) No current shortage Acetazolamide Partial shortage 1 of 3 reported products affected · est. return Jan 1, 2027

Guides: what to do when your medication is in shortage · how to read shortage reports

Data reflects reports manufacturers are legally required to file with Health Canada, republished with per-drug aggregation by rxstat. Estimated end dates are supplied by manufacturers and frequently change. This page describes drug supply only and is not medical advice; never stop or switch a medication without speaking to your pharmacist or prescriber.