Source: Health Canada shortage reports · Updated Jul 9, 2026
Some Bivalirudin products are in shortage in Canada (1 of 3 reported products), while others remain available. Your pharmacy may be able to substitute an unaffected manufacturer.
A blood thinner used during certain heart procedures to prevent clots.
Products affected
1 / 3
Reports on file
9
Talk to a pharmacist
Pharmacists can substitute an unaffected manufacturer's version, adjust strengths, and in most provinces adapt or renew a prescription on the spot.
Independent services, not affiliated with rxstat; referral fees may apply. Free options exist depending on your province. In an emergency call 911; free health advice at 811.
Shortage history
Shortage history (red bands = periods in shortage).
Reports by product
The DIN is printed on your prescription label.
Active shortage
BIVALIRUDIN INJECTION
5MG · SOLUTION · AVIR PHARMA INC.
DIN 02505517 · since ?, est. end Jun 30, 2026 · Delay in shipping of the drug.
Resolved
ANGIOMAX
250MG · POWDER FOR SOLUTION · SANDOZ CANADA INCORPORATED
DIN 02246533 · ended Mar 16, 2026 · Disruption of the manufacture of the drug.
Discontinued
ANGIOMAX
250MG · POWDER FOR SOLUTION · SANDOZ CANADA INCORPORATED
DIN 02246533
Resolved
BIVALIRUDIN INJECTION
5MG · SOLUTION · AVIR PHARMA INC.
DIN 02505517 · ended Apr 23, 2025 · Delay in shipping of the drug.
Resolved
BIVALIRUDIN FOR INJECTION
250MG · POWDER FOR SOLUTION · FRESENIUS KABI CANADA LTD
DIN 02435268 · ended Nov 17, 2023 · Disruption of the manufacture of the drug.
Resolved
BIVALIRUDIN INJECTION
5MG · SOLUTION · AVIR PHARMA INC.
DIN 02505517 · ended Feb 24, 2023 · Delay in shipping of the drug.
Resolved
BIVALIRUDIN FOR INJECTION
250MG · POWDER FOR SOLUTION · FRESENIUS KABI CANADA LTD
DIN 02435268 · ended Dec 19, 2022 · Disruption of the manufacture of the drug.
Resolved
ANGIOMAX
250MG · POWDER FOR SOLUTION · SANDOZ CANADA INCORPORATED
DIN 02246533 · ended Dec 16, 2022 · Demand increase for the drug.
Resolved
BIVALIRUDIN FOR INJECTION
250MG · POWDER FOR SOLUTION · FRESENIUS KABI CANADA LTD
DIN 02435268 · ended Jan 21, 2022 · Demand increase for the drug.
What's happening
Bivalirudin is currently affected by an active shortage report filed with Health Canada by AVIR PHARMA INC..
The reported cause is: delay in shipping of the drug. Manufacturers must report shortages, but end-date estimates are their own projections and often move.
If your usual product is affected, a pharmacist is the fastest route to a solution: they can dispense an unaffected manufacturer's equivalent when one exists, and in most provinces can adapt doses or substitute a therapeutic alternative without a new appointment.
Bivalirudin is classified under “ANTITHROMBOTIC AGENTS” (ATC B01AE).
Recent changes
No changes recorded yet.
Common questions
What is Bivalirudin used for?
A blood thinner used during certain heart procedures to prevent clots.
When will Bivalirudin be back in stock in Canada?
Manufacturers have not provided a reliable end date. This page updates automatically as soon as an estimate is filed.
Why is Bivalirudin in shortage?
See the reports above; manufacturers must state a reason (most commonly manufacturing disruption or a surge in demand) when filing with Health Canada.
What can my pharmacist do about it?
Often quite a lot: substitute an equivalent product from an unaffected manufacturer, adjust quantities, or in most provinces adapt or renew prescriptions on the spot. Call your pharmacy before visiting, and call 811 for free health advice.
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Drugs in the same therapeutic class, best-supplied first. These are not automatic substitutes: only your pharmacist or prescriber can judge whether a switch makes sense for you.
Data reflects reports manufacturers are legally required to file with Health Canada, republished with per-drug aggregation by rxstat. Estimated end dates are supplied by manufacturers and frequently change. This page describes drug supply only and is not medical advice; never stop or switch a medication without speaking to your pharmacist or prescriber.