rxstat › Shortages › Arsenic Trioxide

Arsenic Trioxide (Trisenox) shortage status

Partial shortage

Source: Health Canada shortage reports · Updated Jul 9, 2026

Some Arsenic Trioxide products are in shortage in Canada (1 of 3 reported products), while others remain available. Your pharmacy may be able to substitute an unaffected manufacturer.

A chemotherapy medication used to treat acute promyelocytic leukemia.

Products affected
1 / 3
In shortage since
May 13, 2020
Reports on file
5
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Pharmacists can substitute an unaffected manufacturer's version, adjust strengths, and in most provinces adapt or renew a prescription on the spot.
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Shortage history

2023 2024 2025 2026

Shortage history (red bands = periods in shortage).

Reports by product

The DIN is printed on your prescription label.

Active shortage
TRISENOX
10MG · SOLUTION · TEVA CANADA LIMITED
DIN 02407833 · since May 13, 2020, no end estimate · Item is to be discontinued - TRISENOX 12MG/6ML 10X6ML INJ SOL is now available.
Resolved
ARSENIC TRIOXIDE FOR INJECTION
1MG · SOLUTION · STERIMAX INC
DIN 02492768 · ended Jan 20, 2026 · Disruption of the manufacture of the drug.
Resolved
ARSENIC TRIOXIDE FOR INJECTION
10MG · SOLUTION · SANDOZ CANADA INCORPORATED
DIN 02513420 · ended Feb 23, 2026 · Demand increase for the drug.
Resolved
ARSENIC TRIOXIDE FOR INJECTION
10MG · SOLUTION · SANDOZ CANADA INCORPORATED
DIN 02513420 · ended Dec 9, 2024 · Disruption of the manufacture of the drug.
Resolved
TRISENOX
1MG · SOLUTION · LUNDBECK CANADA INC
DIN 02407833 · ended Jul 24, 2018 · Disruption of the manufacture of the drug.

What's happening

Arsenic Trioxide is currently affected by an active shortage report filed with Health Canada by TEVA CANADA LIMITED.

The reported cause is: item is to be discontinued - trisenox 12mg/6ml 10x6ml inj sol is now available. Manufacturers must report shortages, but end-date estimates are their own projections and often move.

If your usual product is affected, a pharmacist is the fastest route to a solution: they can dispense an unaffected manufacturer's equivalent when one exists, and in most provinces can adapt doses or substitute a therapeutic alternative without a new appointment.

Arsenic Trioxide is classified under “OTHER ANTINEOPLASTIC AGENTS” (ATC L01XX).

Recent changes

Common questions

What is Arsenic Trioxide used for?

A chemotherapy medication used to treat acute promyelocytic leukemia.

When will Arsenic Trioxide be back in stock in Canada?

Manufacturers have not provided a reliable end date. This page updates automatically as soon as an estimate is filed.

Why is Arsenic Trioxide in shortage?

See the reports above; manufacturers must state a reason (most commonly manufacturing disruption or a surge in demand) when filing with Health Canada.

What can my pharmacist do about it?

Often quite a lot: substitute an equivalent product from an unaffected manufacturer, adjust quantities, or in most provinces adapt or renew prescriptions on the spot. Call your pharmacy before visiting, and call 811 for free health advice.

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Possible alternatives in the same class (other antineoplastic agents)

Drugs in the same therapeutic class, best-supplied first. These are not automatic substitutes: only your pharmacist or prescriber can judge whether a switch makes sense for you.

Aminolevulinic Acid (Levulan Kerastick) No current shortage Anagrelide (Agrylin) No current shortage Hydroxyurea (Hydrea) No current shortage Ipilimumab (Yervoy) No current shortage Methyl Aminolevulinate (Metvix) No current shortage Pegaspargase (Oncaspar) No current shortage

Guides: what to do when your medication is in shortage · how to read shortage reports

Data reflects reports manufacturers are legally required to file with Health Canada, republished with per-drug aggregation by rxstat. Estimated end dates are supplied by manufacturers and frequently change. This page describes drug supply only and is not medical advice; never stop or switch a medication without speaking to your pharmacist or prescriber.