rxstat › Shortages › Alprostadil

Alprostadil shortage status

Widespread shortage

Source: Health Canada shortage reports · Updated Jul 9, 2026

Alprostadil is in a widespread shortage in Canada. 3 of 5 reported products are affected. Manufacturers have not committed to a recovery date.
Products affected
3 of 5
In shortage since
Jul 22, 2021
Reports on file
19
Talk to your pharmacist. Pharmacists can often substitute another manufacturer's version, a different strength, or (in most provinces) adapt or renew a prescription on the spot. Your free provincial health line is 811.

Reports by product

Active shortage
MUSE
250MCG · SUPPOSITORY · PALADIN LABS INC.
DIN 02238593 · since ?, no end estimate · Disruption of the manufacture of the drug.
Active shortage
MUSE
500MCG · SUPPOSITORY · PALADIN LABS INC.
DIN 02238594 · since Jun 3, 2022, no end estimate · Disruption of the manufacture of the drug.
Active shortage
MUSE
1000MCG · SUPPOSITORY · PALADIN LABS INC.
DIN 02238595 · since Jul 22, 2021, no end estimate · Delay in shipping of the drug.
Anticipated
CAVERJECT STERILE POWDER
20MCG · POWDER FOR SOLUTION LIQUID KIT · PFIZER CANADA ULC
DIN 02215756 · Disruption of the manufacture of the drug.
Resolved
CAVERJECT STERILE POWDER
20MCG · POWDER FOR SOLUTION LIQUID KIT · PFIZER CANADA ULC
DIN 02215756 · ended May 14, 2024 · Disruption of the manufacture of the drug.
Resolved
PROSTIN VR STERILE SOLUTION
500MCG · SOLUTION · PFIZER CANADA ULC
DIN 00559253 · ended Dec 8, 2023 · Disruption of the manufacture of the drug.
Resolved
PROSTIN VR STERILE SOLUTION
500MCG · SOLUTION · PFIZER CANADA ULC
DIN 00559253 · ended May 12, 2022 · Disruption of the manufacture of the drug.
Resolved
MUSE
250MCG · SUPPOSITORY · PALADIN LABS INC.
DIN 02238593 · ended Mar 22, 2022 · Disruption of the manufacture of the drug.
Resolved
MUSE
500MCG · SUPPOSITORY · PALADIN LABS INC.
DIN 02238594 · ended Feb 11, 2022 · Delay in shipping of the drug.
Resolved
MUSE
250MCG · SUPPOSITORY · PALADIN LABS INC
DIN 02238593 · ended Apr 28, 2021 · Delay in shipping of the drug.
Resolved
MUSE
1000MCG · SUPPOSITORY · PALADIN LABS INC
DIN 02238595 · ended Mar 26, 2021 · Delay in shipping of the drug.
Resolved
CAVERJECT STERILE POWDER
23.2MCG · KIT LIQUID POWDER FOR SOLUTION · PFIZER CANADA ULC
DIN 02215756 · ended Oct 26, 2020 · Disruption of the manufacture of the drug.

Showing 12 of 19 reports. All reports are on file with Health Canada.

What's happening

Alprostadil is currently affected by 3 active shortage reports filed with Health Canada by PALADIN LABS INC..

The reported causes are: disruption of the manufacture of the drug; delay in shipping of the drug. Manufacturers must report shortages, but end-date estimates are their own projections and often move.

If your usual product is affected, a pharmacist is the fastest route to a solution: they can dispense an unaffected manufacturer's equivalent when one exists, and in most provinces can adapt doses or substitute a therapeutic alternative without a new appointment.

Alprostadil is classified under “OTHER UROLOGICALS, INCL ANTISPASMODICS” (ATC G04BE).

Recent changes

Common questions

When will Alprostadil be back in stock in Canada?

Manufacturers have not provided a reliable end date. This page updates automatically as soon as an estimate is filed.

Why is Alprostadil in shortage?

See the reports above; manufacturers must state a reason (most commonly manufacturing disruption or a surge in demand) when filing with Health Canada.

What can my pharmacist do about it?

Often quite a lot: substitute an equivalent product from an unaffected manufacturer, adjust quantities, or in most provinces adapt or renew prescriptions on the spot. Call your pharmacy before visiting, and call 811 for free health advice.

Related drugs (other urologicals, incl antispasmodics)

Widespread shortageFlavoxate2 of 2 reported products affectedWidespread shortageMirabegron2 of 2 reported products affected · est. return Jul 3, 2026Widespread shortageTolterodine8 of 16 reported products affected · est. return Sep 8, 2026Partial shortageDarifenacin1 of 6 reported products affected · est. return Jul 10, 2026Partial shortageFesoterodine1 of 4 reported products affected · est. return Jan 29, 2027Partial shortageOxybutynin Chloride2 of 11 reported products affected

All other urologicals, incl antispasmodics shortage statuses →

Guides: what to do when your medication is in shortage · how to read shortage reports

Data reflects reports manufacturers are legally required to file with Health Canada, republished with per-drug aggregation by rxstat. Estimated end dates are supplied by manufacturers and frequently change. This page describes drug supply only and is not medical advice; never stop or switch a medication without speaking to your pharmacist or prescriber.