rxstat › Shortages › Adefovir Dipivoxil

Adefovir Dipivoxil (Hepsera) shortage status

Partial shortage

Source: Health Canada shortage reports · Updated Jul 9, 2026

Some Adefovir Dipivoxil products are in shortage in Canada (1 of 2 reported products), while others remain available. Your pharmacy may be able to substitute an unaffected manufacturer.

An antiviral medication used to treat chronic hepatitis B infection.

Products affected

1 / 2

In shortage since

Jun 30, 2022

Reports on file

Talk to a pharmacist

Pharmacists can substitute an unaffected manufacturer's version, adjust strengths, and in most provinces adapt or renew a prescription on the spot.

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Need your prescription switched?

If your product stays unavailable, an online doctor can assess your situation and prescribe an alternative.

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Shortage history

Shortage history (red bands = periods in shortage).

Reports by product

The DIN is printed on your prescription label.

Active shortage

AA-ADEFOVIR

10MG · TABLET · AA PHARMA INC

DIN 02420333 · since Jun 30, 2022, no end estimate · Disruption of the manufacture of the drug.

Discontinued

HEPSERA

10MG · TABLET · GILEAD SCIENCES CANADA INC

DIN 02247823

Resolved

APO-ADEFOVIR

10MG · TABLET · APOTEX INC

DIN 02420333 · ended Aug 13, 2020 · Disruption of the manufacture of the drug.

What's happening

Adefovir Dipivoxil is currently affected by an active shortage report filed with Health Canada by AA PHARMA INC.

The reported cause is: disruption of the manufacture of the drug. Manufacturers must report shortages, but end-date estimates are their own projections and often move.

If your usual product is affected, a pharmacist is the fastest route to a solution: they can dispense an unaffected manufacturer's equivalent when one exists, and in most provinces can adapt doses or substitute a therapeutic alternative without a new appointment.

Adefovir Dipivoxil is classified under “DIRECT ACTING ANTIVIRALS” (ATC J05AF).

Recent changes

No changes recorded yet.

Common questions

What is Adefovir Dipivoxil used for?

An antiviral medication used to treat chronic hepatitis B infection.

When will Adefovir Dipivoxil be back in stock in Canada?

Manufacturers have not provided a reliable end date. This page updates automatically as soon as an estimate is filed.

Why is Adefovir Dipivoxil in shortage?

See the reports above; manufacturers must state a reason (most commonly manufacturing disruption or a surge in demand) when filing with Health Canada.

What can my pharmacist do about it?

Often quite a lot: substitute an equivalent product from an unaffected manufacturer, adjust quantities, or in most provinces adapt or renew prescriptions on the spot. Call your pharmacy before visiting, and call 811 for free health advice.

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Possible alternatives in the same class (direct acting antivirals)

Drugs in the same therapeutic class, best-supplied first. These are not automatic substitutes: only your pharmacist or prescriber can judge whether a switch makes sense for you.

Inosine Pranobex (Imunovir) No current shortage Letermovir (Prevymis) No current shortage Nirmatrelvir Ritonavir (Paxlovid) No current shortage Atazanavir (Reyataz) Partial shortage 3 of 8 reported products affected Baloxavir Marboxil (Xofluza) Partial shortage 1 of 1 reported products affected Darunavir (Prezista) Partial shortage 2 of 9 reported products affected · est. return Jul 31, 2026

Guides: what to do when your medication is in shortage · how to read shortage reports

Data reflects reports manufacturers are legally required to file with Health Canada, republished with per-drug aggregation by rxstat. Estimated end dates are supplied by manufacturers and frequently change. This page describes drug supply only and is not medical advice; never stop or switch a medication without speaking to your pharmacist or prescriber.