Acetylcholine Chloride (Miochol-E, Miochol E) shortage status
Partial shortage
Source: Health Canada shortage reports · Updated Jul 17, 2026
Some Acetylcholine Chloride products are in shortage in Canada (1 of 1 reported products), while others remain available. Your pharmacy may be able to substitute an unaffected manufacturer. The latest estimate for affected products to return is Oct 1, 2026.
A medication used during eye surgery to quickly constrict the pupil.
Products affected
1 / 1
In shortage since
Dec 4, 2025
Est. full return
Oct 1, 2026
Reports on file
12
Talk to a pharmacist
Pharmacists can substitute an unaffected manufacturer's version, adjust strengths, and in most provinces adapt or renew a prescription on the spot.
Independent services, not affiliated with rxstat; referral fees may apply. Free options exist depending on your province. In an emergency call 911; free health advice at 811.
Shortage history
Shortage history (red bands = periods in shortage).
Reports by product
The DIN is printed on your prescription label.
Active shortage
MIOCHOL-E
20MG · POWDER FOR SOLUTION · BAUSCH & LOMB INC
DIN 02133326 · since Dec 4, 2025, est. end Oct 1, 2026 · Disruption of the manufacture of the drug.
Resolved
MIOCHOL-E
20MG · POWDER FOR SOLUTION · BAUSCH & LOMB INC
DIN 02133326 · ended Oct 29, 2025 · Demand increase for the drug.
Resolved
MIOCHOL-E
20MG · POWDER FOR SOLUTION · BAUSCH & LOMB INC
DIN 02133326 · ended Mar 18, 2025 · Requirements related to complying with good manufacturing practices.
Resolved
MIOCHOL-E
20MG · POWDER FOR SOLUTION · BAUSCH & LOMB INC
DIN 02133326 · ended May 21, 2024 · Requirements related to complying with good manufacturing practices.
Resolved
MIOCHOL-E
20MG · POWDER FOR SOLUTION · BAUSCH & LOMB INC
DIN 02133326 · ended May 3, 2023 · Delay in shipping of the drug.
Resolved
MIOCHOL-E
20MG · POWDER FOR SOLUTION · BAUSCH & LOMB INC
DIN 02133326 · ended Oct 10, 2022 · production delay
Resolved
MIOCHOL-E
20MG · POWDER FOR SOLUTION · BAUSCH & LOMB INC
DIN 02133326 · ended Feb 16, 2022 · API issue
Resolved
MIOCHOL E
20MG · POWDER FOR SOLUTION · BAUSCH & LOMB INC
DIN 02133326 · ended Jul 13, 2021 · delay in production
Resolved
MIOCHOL E
10MG · POWDER FOR SOLUTION · BAUSCH & LOMB INC
DIN 02133326 · ended Apr 21, 2020 · delay in production
Resolved
MIOCHOL E
10MG · POWDER FOR SOLUTION · BAUSCH & LOMB INC
DIN 02133326 · ended Sep 25, 2019 · delay in production
Resolved
MIOCHOL E
10MG · POWDER FOR SOLUTION · BAUSCH & LOMB INC
DIN 02133326 · ended Jun 20, 2018
Resolved
MIOCHOL E
10MG · POWDER FOR SOLUTION · BAUSCH & LOMB INC
DIN 02133326 · ended Jul 14, 2017 · Delay in Manufacturing
What's happening
Acetylcholine Chloride is currently affected by an active shortage report filed with Health Canada by BAUSCH & LOMB INC.
The reported cause is: disruption of the manufacture of the drug. Manufacturers must report shortages, but end-date estimates are their own projections and often move.
If your usual product is affected, a pharmacist is the fastest route to a solution: they can dispense an unaffected manufacturer's equivalent when one exists, and in most provinces can adapt doses or substitute a therapeutic alternative without a new appointment.
Acetylcholine Chloride is classified under “ANTIGLAUCOMA PREPARATIONS AND MIOTICS” (ATC S01EB).
Recent changes
Jul 17, 2026
Estimated end date pushed back : Aug 1, 2026 → Oct 1, 2026
Common questions
What is Acetylcholine Chloride used for?
A medication used during eye surgery to quickly constrict the pupil.
When will Acetylcholine Chloride be back in stock in Canada?
The latest manufacturer estimate is Oct 1, 2026. Estimates are self-reported and often slip; this page updates automatically when they change.
Why is Acetylcholine Chloride in shortage?
See the reports above; manufacturers must state a reason (most commonly manufacturing disruption or a surge in demand) when filing with Health Canada.
What can my pharmacist do about it?
Often quite a lot: substitute an equivalent product from an unaffected manufacturer, adjust quantities, or in most provinces adapt or renew prescriptions on the spot. Call your pharmacy before visiting, and call 811 for free health advice.
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Drugs in the same therapeutic class, best-supplied first. These are not automatic substitutes: only your pharmacist or prescriber can judge whether a switch makes sense for you.
Data reflects reports manufacturers are legally required to file with Health Canada, republished with per-drug aggregation by rxstat. Estimated end dates are supplied by manufacturers and frequently change. This page describes drug supply only and is not medical advice; never stop or switch a medication without speaking to your pharmacist or prescriber.